3--2-phenylbutyronitrile

Base Information

• Chemical Name: 3--2-phenylbutyronitrile
• CAS No.: 225222-59-3
• Molecular Formula: C₁₇H₁₆N₂O
• Molecular Weight: 264.327
• Mol file: 225222-59-3.mol

Synonyms:

Chemical Property of 3--2-phenylbutyronitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3--2-phenylbutyronitrile

There total 1 articles about 3--2-phenylbutyronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-methoxy-aniline (104-94-9) + 1-phenyl-1-cyanopropan-2-one (4468-48-8) → 3--2-phenylbutyronitrile (225222-59-3)

Guidance literature:

With acetic acid; for 0.5h; Heating;

DOI:10.1002/jhet.5570360115

Reference yield: 15.0%

acetic anhydride (108-24-7) + 3--2-phenylbutyronitrile (225222-59-3) → N-acetyl-3-<3-(p-methoxyphenylamino)-3-methyl-2-phenyl>propenamide

Guidance literature:

With perchloric acid; for 0.05h;

DOI:10.1002/jhet.5570360115

Reference yield:

3--2-phenylbutyronitrile (225222-59-3) → 1-(4-methoxy-phenyl)-2,6-dimethyl-5-phenyl-1H-pyrimidin-4-one; compound with perchloric acid

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / 70 percent aq. perchloric acid / 0.05 h

2: HClO₄, AcOH

With perchloric acid; acetic acid;

DOI:10.1002/jhet.5570360115

upstream raw materials:

4-methoxy-aniline

1-phenyl-1-cyanopropan-2-one