(2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone

Base Information Edit

Chemical Name:(2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone
CAS No.:105192-42-5
Molecular Formula:C12H9ClN2O
Molecular Weight:232.669
Hs Code.:
European Community (EC) Number:683-671-8
Nikkaji Number:J3.450.175K
Mol file:105192-42-5.mol

Synonyms:105192-42-5;(2-amino-5-chlorophenyl)-4-pyridinylMethanone;SCHEMBL28060;(2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone;FPRZFKUEVICJMQ-UHFFFAOYSA-N;4-(2-Amino-5-chlorobenzoyl)pyridine;FT-0708967;(2-Amino-5-chlorophenyl)(4-pyridyl)methanone;(2-amino-5-chlorophenyl) (pyridin-4-yl)methanone;(2-amino-5-chloro-phenyl)-pyridin -4-yl-methanone

Suppliers and Price of (2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone Edit

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:232.0403406
Heavy Atom Count:16
Complexity:253

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)C(=O)C2=CC=NC=C2)N

Technology Process of (2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone

There total 7 articles about (2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 100-48-1
pyridine-4-carbonitrile

: 106-47-8
4-chloro-aniline

: 105192-42-5
(2-amino-5-chlorophenyl)(pyridin-4-yl)methanone

Guidance literature:: With aluminium trichloride; boron trichloride; In various solvent(s); RT, 20 min; reflux, 6 h;

Reference yield: 65.0%

: 52482-36-7
morpholin-4-yl(pyridin-4-yl)methanone

: 65854-91-3
N-(4-chlorophenyl)-2,2-dimethylpropionamide

: 105192-42-5
(2-amino-5-chlorophenyl)(pyridin-4-yl)methanone

Guidance literature:: N-(4-chlorophenyl)-2,2-dimethylpropionamide; With n-butyllithium; In tetrahydrofuran; hexane; at -30 - -20 ℃; for 2h; Inert atmosphere;

morpholin-4-yl(pyridin-4-yl)methanone; In tetrahydrofuran; hexane; at 15 - 25 ℃; for 4h; Inert atmosphere;

With methanol; potassium hydroxide; In water; at 55 - 65 ℃; for 4h;