1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane

Base Information

• Chemical Name: 1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane
• CAS No.: 104684-71-1
• Molecular Formula: C₂₁H₂₇N₃O₃
• Molecular Weight: 369.464

Synonyms:

Chemical Property of 1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane

There total 1 articles about 1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-(4-aminophenoxy)-3-1-4-(2-methoxyphenyl)-piperazinyl>>propane (104655-08-5) + formic acid ethyl ester (109-94-4) → 1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane (104684-71-1)

Guidance literature:

for 8h; Heating;

Reference yield: 73.0%

1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane (104684-71-1) → 1-<4-(N-Methylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride (104655-23-4)

Guidance literature:

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; 1.) THF, 8h, reflux, 2.) ether;

Reference yield:

1-<4-(N-Formylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane (104684-71-1) → 1-<4-(N-Methylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane (104655-09-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 8h; Heating;

upstream raw materials:

1-(4-aminophenoxy)-3-1-4-(2-methoxyphenyl)-piperazinyl>>propane

formic acid ethyl ester

Downstream raw materials:

1-<4-(N-Methylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride

1-<4-(N-Methylaminophenoxy)>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane

N-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-N-methyl-formamide

1-<4-(N,N-dimethylamino)phenoxy>-3-1-4-(2-methoxyphenyl)piperazinyl>>propane hydrochloride

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