(3,5-Diethyl-phenyl)-acetonitrile

Base Information

• Chemical Name: (3,5-Diethyl-phenyl)-acetonitrile
• CAS No.: 198623-54-0
• Molecular Formula: C₁₂H₁₅N
• Molecular Weight: 173.258
• Mol file: 198623-54-0.mol

Synonyms:

Chemical Property of (3,5-Diethyl-phenyl)-acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3,5-Diethyl-phenyl)-acetonitrile

There total 6 articles about (3,5-Diethyl-phenyl)-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-diethylbenzoic acid (3854-90-8) → (3,5-Diethyl-phenyl)-acetonitrile (198623-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / LiAlH₄ / tetrahydrofuran

2: 1) SOCl₂ / 1) C₆H₆, 2) aq. EtOH

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;

DOI:10.1016/S0960-894X(97)00445-9

Reference yield:

1,3,5-triethylbenzene (102-25-0) → (3,5-Diethyl-phenyl)-acetonitrile (198623-54-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 88 percent / NBS / CCl₄

2: 100 percent / BaCO₃ / dioxane; H₂O

3: 53 percent / 8 N Jones reagent / acetone

4: 90 percent / Br₂, NaOH / H₂O; dioxane

5: 92 percent / LiAlH₄ / tetrahydrofuran

6: 1) SOCl₂ / 1) C₆H₆, 2) aq. EtOH

With sodium hydroxide; N-Bromosuccinimide; lithium aluminium tetrahydride; thionyl chloride; jones reagent; bromine; barium carbonate; In tetrahydrofuran; 1,4-dioxane; tetrachloromethane; water; acetone;

DOI:10.1016/S0960-894X(97)00445-9

Reference yield:

3′,5′-diethylacetophenone (52095-17-7) → (3,5-Diethyl-phenyl)-acetonitrile (198623-54-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / Br₂, NaOH / H₂O; dioxane

2: 92 percent / LiAlH₄ / tetrahydrofuran

3: 1) SOCl₂ / 1) C₆H₆, 2) aq. EtOH

With sodium hydroxide; lithium aluminium tetrahydride; thionyl chloride; bromine; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1016/S0960-894X(97)00445-9

upstream raw materials:

potassium cyanide

(3,5-diethylphenyl)methanol

1,3,5-triethylbenzene

3,5-diethylbenzoic acid