azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid

Base Information

• Chemical Name: azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid
• CAS No.: 81914-60-5
• Molecular Formula: C₇H₃ClN₄O₄
• Molecular Weight: 242.578
• Mol file: 81914-60-5.mol

Synonyms:

Chemical Property of azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid

There total 2 articles about azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-3-hydroxy-4-chlorobenzohydrazide → azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid (81914-60-5)

Guidance literature:

With hydrogenchloride; sodium nitrite; In acetic acid; at -5 ℃;

Reference yield:

methyl 4-chloro-2-nitro-3-hydroxybenzoate (20689-62-7) → azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid (81914-60-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / methanol

2: sodium nitrite; 15percent aq. HCl / acetic acid / -5 °C

With hydrogenchloride; hydrazine hydrate; sodium nitrite; In methanol; acetic acid;

Reference yield: 29.0%

azide of 2-nitro-3-hydroxy-4-chlorobenzoic acid (81914-60-5) + 2-amino-2-hydroxymethyl-1,3-propanediol (77-86-1) → N-(2-nitro-3-hydroxy-4-chlorobenzoyl)tris(hydroxymethyl)methylamine (81914-62-7)

Guidance literature:

In water; for 24h; Ambient temperature;

upstream raw materials:

methyl 4-chloro-2-nitro-3-hydroxybenzoate

Downstream raw materials:

N-(2-nitro-3-hydroxy-4-chlorobenzoyl)tris(hydroxymethyl)methylamine