1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

Base Information

Chemical Name:1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose
CAS No.:130130-43-7
Molecular Formula:C₄₅H₅₈O₁₃Si₂
Molecular Weight:863.119
Hs Code.:

Synonyms:

Suppliers and Price of 1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

There total 2 articles about 1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 114129-74-7
1,6-anhydro-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

: 98-88-4
benzoyl chloride

: 130130-43-7
1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

Guidance literature:: With pyridine; Ambient temperature;

Reference yield:

: 28868-67-9
2,3-di-O-acetyl-1,6-anhydro-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-β-D-glycopyranose

: 69304-37-6
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

: 1125-88-8
benzaldehyde dimethyl acetal

: 98-88-4
benzoyl chloride

: 130130-43-7
1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

Guidance literature:: Yield given. Multistep reaction;

Reference yield:

: 130130-43-7
1,6-anhydro-2,3-di-O-benzoyl-4',6'-O-benzylidene-2',3'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-maltose

: 1L-(1,6/2,3)-3-amino-2-(2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyloxy)-6-(glycyl(methyl)amino)cyclohexanol

Guidance literature:: Multi-step reaction with 26 steps

1: 41 g / tetraethylammonium chloride, aq. potassium fluoride dihydrate / acetonitrile; H₂O / 6 h / Ambient temperature

2: 88 percent / pyridine / 16 h / 0 °C

3: 80 g / methanolic sodium methoxide / tetrahydrofuran; methanol / 1 h / Ambient temperature

4: 75 percent / pyridine / CH₂Cl₂ / 9 h / 0 °C

5: 84 percent / tetrabutylammonium hydrogen sulphate, aq. sodium hydroxide / toluene / -15 - -10 °C

6: 80 percent / methanolic sodium methoxide / CH₂Cl₂; methanol / 72 h / 0 °C

7: 88 percent / sodium hydride, tetrabutylammonium iodide / tetrahydrofuran / 6 h / Ambient temperature

8: 71 percent / sodium azide, ammonium chloride / aq. ethanol / 11 h / 80 - 90 °C

9: 1.) acetic anhydride, aq. sodium acetate 2.) sodium borohydride / 1.) DMSO a) 12 h, RT_. b) 3 h, 0 deg C 2.) dichloromethane-ethanol-water, 0 deg C, 30 min

10: 1.) lithium aluminium hydride, water, aq. sodium hydroxide 2.) saturated aq. sodium hydrogen carbonate / 1.) diethyl ether, RT, 2 h 2.) THF-methanol, 0 deg C, 2 h

11: 2.1 g / DMAP, pyridine / acetonitrile / 2 h / Ambient temperature

12: 96 percent / tributyltin hydride, AIBN / toluene / 1.5 h / 80 °C

13: 88 percent / acetic acid, water / 2 h / 60 - 70 °C

14: 62 percent / pyridine / 60 h / Ambient temperature

15: 91 percent / sodium azide / dimethylformamide / 22 h / 100 °C

16: 74 percent / barium oxide, barium hydroxide octahydrate / dimethylformamide / Ambient temperature

17: 1.) zinc iodide, aq. sodium hydrogen carbonate 2.) saturated aq. sodium hydrogen carbonate / 1.) 1,2-dichloroethane 2.) THF-methanol, 0 deg C, 1 h

18: 85 percent

19: lithium iodide

20: DBU

21: 1.) mercury(II) chloride 2.) methanesulphonyl chloride, pyridine / 1.) acetone-water, RT, 3 d 2.) a) -15 deg C b) RT

22: 1.) cerium(III) chloride heptahydrate, sodium borohydride 2.) TPP, hydrazoic acid, DEAD

23: potassium azodicarboxylate-acetic acid / acetonitrile / 3 h / Ambient temperature

24: DDQ / CH₂Cl₂; H₂O / 3 h / Ambient temperature

25: 1.) DMSO-TFAA, triethylamine 2.) acetic acid, sodium cyanoborohydride

26: 75 percent / H₂ / 10percent palladium on carbon / methanol; HCl / 33 h / Ambient temperature

With pyridine; dmap; potassium fluoride; sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; hydrogen azide; sodium azide; cerium(III) chloride; barium hydroxide octahydrate; 2,2'-azobis(isobutyronitrile); ammonium chloride; tetraethylammonium chloride; water; hydrogen; tri-n-butyl-tin hydride; sodium methylate; sodium acetate; tetra(n-butyl)ammonium hydrogensulfate; potassium diazodicarboxylate; acetic anhydride; thiamine diphosphate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; sodium hydrogencarbonate; acetic acid; dimethyl sulfoxide; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic anhydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; mercury dichloride; zinc(II) iodide; barium(II) oxide; lithium iodide; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; hydrogenchloride; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;