Anthra(2,1-b)furan, 8-methoxy-2-nitro-

Base Information

• Chemical Name: Anthra(2,1-b)furan, 8-methoxy-2-nitro-
• CAS No.: 104662-33-1
• Deprecated CAS: 113737-18-1
• Molecular Formula: C₁₇H₁₁NO₄
• Molecular Weight: 293.279
• DSSTox Substance ID: DTXSID10146640
• Nikkaji Number: J547.997E
• Wikidata: Q83011490
• ChEMBL ID: CHEMBL6922
• Mol file: 104662-33-1.mol

Synonyms:Anthra(2,1-b)furan, 8-methoxy-2-nitro-;104662-33-1;BRN 4515557;8-Methoxy-2-nitroanthra(2,1-b)furan;2-Nitro-8-methoxyanthara(2,1-b)furan;R-7707;CHEMBL6922;DTXSID10146640

Chemical Property of Anthra(2,1-b)furan, 8-methoxy-2-nitro-

Chemical Property:

• Vapor Pressure: 4.72E-10mmHg at 25°C
• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 293.06880783
• Heavy Atom Count: 22
• Complexity: 437

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)C=C3C(=C2)C=CC4=C3C=C(O4)[N+](=O)[O-]

Technology Process of Anthra(2,1-b)furan, 8-methoxy-2-nitro-

There total 5 articles about Anthra(2,1-b)furan, 8-methoxy-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

bromonitromethane (563-70-2) + formyl-1 hydroxy-2 methoxy-6 anthracene (104662-37-5) → methoxy-8 nitro-2 anthra<2,1-b>furanne (104662-33-1,113737-18-1)

Guidance literature:

With potassium fluoride; In methanol; for 45h; Heating;

DOI:10.1002/jhet.5570220324

Reference yield:

anthracene-2,6-diol (101488-73-7) → methoxy-8 nitro-2 anthra<2,1-b>furanne (104662-33-1,113737-18-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) chlorure stannique ahydre, 2.) aq. acide chlorhydrique (0.1 N), / 1.) dichloromethane, 0 deg C, 6 hrs., 2.) 30 min.,

2: 97.5 percent / methanol / 1 h / Heating

3: 30 percent / carbonate de potassium / acetone / 4 h / Heating

4: 70 percent / chlorure de aluminium / CH₂Cl₂ / 29 h / Ambient temperature

5: 34 percent / fluorure de potassium / methanol / 45 h / Heating

With hydrogenchloride; potassium fluoride; chlorure de aluminium; chlorure stannique ahydre; potassium carbonate; In methanol; dichloromethane; acetone;

DOI:10.1002/jhet.5570220324

Reference yield:

formyl-1 dihydroxy-2,6 anthracene (104662-35-3) → methoxy-8 nitro-2 anthra<2,1-b>furanne (104662-33-1,113737-18-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 30 percent / carbonate de potassium / acetone / 4 h / Heating

2: 70 percent / chlorure de aluminium / CH₂Cl₂ / 29 h / Ambient temperature

3: 34 percent / fluorure de potassium / methanol / 45 h / Heating

With potassium fluoride; chlorure de aluminium; potassium carbonate; In methanol; dichloromethane; acetone;

DOI:10.1002/jhet.5570220324

upstream raw materials:

bromonitromethane

formyl-1 hydroxy-2 methoxy-6 anthracene

anthracene-2,6-diol

formyl-1 dihydroxy-2,6 anthracene