2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone

Base Information

• Chemical Name: 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone
• CAS No.: 877208-94-1
• Molecular Formula: C₂₃H₂₈O₃
• Molecular Weight: 352.474
• Mol file: 877208-94-1.mol

Synonyms:

Chemical Property of 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone

There total 3 articles about 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(trans-bicyclohexylyl-(4))-acetic acid (106839-02-5) → 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone (877208-94-1)

Guidance literature:

With thionyl chloride; Behandeln des Reaktionsprodukts in Aether mit wss.H₂O₂ unterhalb 0grad und mit wss.NaOH unterhalb 5grad und Eintragen des Reaktionsprodukts mit 2-Hydroxy-naphthochinon-(1.4) in Essigsaeure bei 90grad;

Reference yield:

(trans)-2-(4-phenylcyclohexyl)acetic acid (52092-29-2) → 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone (877208-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; platinum / Hydrogenation

2: SOCl₂ / Behandeln des Reaktionsprodukts in Aether mit wss.H₂O₂ unterhalb 0grad und mit wss.NaOH unterhalb 5grad und Eintragen des Reaktionsprodukts mit 2-Hydroxy-naphthochinon-(1.4) in Essigsaeure bei 90grad

With thionyl chloride; ethanol; platinum;

Reference yield:

bicyclohexylyl-(4)-acetic acid ethyl ester → 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone (877208-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Hydrolysis

2: SOCl₂ / Behandeln des Reaktionsprodukts in Aether mit wss.H₂O₂ unterhalb 0grad und mit wss.NaOH unterhalb 5grad und Eintragen des Reaktionsprodukts mit 2-Hydroxy-naphthochinon-(1.4) in Essigsaeure bei 90grad

With thionyl chloride;

upstream raw materials:

(trans-bicyclohexylyl-⁽⁴⁾)-acetic acid

(trans)-2-(4-phenylcyclohexyl)acetic acid