52092-29-2

Basic information

• Product Name: Cyclohexaneacetic acid, 4-phenyl-, trans-
• Synonyms: Cyclohexaneacetic acid, 4-phenyl-, trans-;2-((1r,4r)-4-phenylcyclohexyl)acetic acid;trans-4-Phenylcyclohexaneacetic acid
• CAS NO: 52092-29-2
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.29152
• Mol File: 52092-29-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexaneacetic acid, 4-phenyl-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexaneacetic acid, 4-phenyl-, trans-(52092-29-2)
• EPA Substance Registry System: Cyclohexaneacetic acid, 4-phenyl-, trans-(52092-29-2)

Safety Data

• Hazardous Substances Data: 52092-29-2(Hazardous Substances Data)

Upstream product

• 18294-87-6 1-cyclohexenylacetic acid 
• 7446-70-0 aluminium trichloride 
• 24871-12-3 trans-hexahydro-2(3H)-benzofuranone 
• 71-43-2 benzene 
• 411238-92-1 ethyl 2-(4-phenylcyclohexyl)acetate 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 115880-04-1 ethyl 2-(4-phenylcyclohexylidene)acetate 
• 776-69-2 4-phenylcyclohexane-1,3-dione 
• 5326-50-1 (1-hydroxycyclohexyl)acetic acid ethyl ester 
• 68670-32-6 trans-4-Phenylcyclohexylessigsaeuremethylester 
• 64-18-6 formic acid 
• 87143-17-7 4-phenyl-1-methylenecyclohexane 
• 1031336-66-9 trans-ethyl 2-4-((4-(hydroxymethyl)phenyl)cyclohexyl)acetate 
• 1552-91-6 cyclohexylideneacetic acid 

Downstream Products

• 877208-94-1 2trans-bicyclohexyl-4-ylmethyl-3-hydroxy-[1,4]naphthoquinone 
• 1031336-66-9 trans-ethyl 2-4-((4-(hydroxymethyl)phenyl)cyclohexyl)acetate 
• 107623-45-0 (trans-4-phenyl-cyclohexyl)-acetic acid-chloride 

Relevant articles and documents

IMMUNOREGULATORY AGENTS

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Synthesis and pharmacological study of diphenylalkylamines with cycloaliphatic residues; new coronary vasodilators

The paper describes the synthesis and the pharmacological evaluation of some derivatives of prenylamine, all with a cycloaliphatic ring within or instead of the isopropylamine moiety. Where the alicyclic ring had a bulky substituent in para were more active than prenylamine as coronary vasodilators on isolated guinea pig heart (Langendorff). The most interesting derivative was MG 8926 [N (3,3 diphenylpropyl) α methyl β cyclohexylethylamine], which was more active than prenylamine on Langendorff's heart and in enhancing the pressor response to catecholamines and inhibiting the isoprenaline induced hypotension. Moreover, it had almost the same effects as prenylamine as spasmolytic, local and general anesthetic, on heart rate and arterial pressure and against coronary spasm from pitressin.