2,4,5,6-tetrafluoropyridine-3-carboxylic Acid

Base Information

• Chemical Name: 2,4,5,6-tetrafluoropyridine-3-carboxylic Acid
• CAS No.: 3512-15-0
• Molecular Formula: C₆HF₄NO₂
• Molecular Weight: 195.073
• DSSTox Substance ID: DTXSID901250738
• Nikkaji Number: J1.253.682H

Synonyms:3512-15-0;2,4,5,6-tetrafluoropyridine-3-carboxylic Acid;2,4,5,6-tetrafluoronicotinicacid;DTXSID901250738;2,4,5,6-tetrafluoronicotinic acid;2,4,5,6-Tetrafluoro-3-pyridinecarboxylic acid

Chemical Property of 2,4,5,6-tetrafluoropyridine-3-carboxylic Acid

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 194.99434092
• Heavy Atom Count: 13
• Complexity: 215

Purity/Quality:

2,4,5,6-TETRAFLUORO-NICOTINIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1(=C(C(=C(N=C1F)F)F)F)C(=O)O

Technology Process of 2,4,5,6-tetrafluoropyridine-3-carboxylic Acid

There total 2 articles about 2,4,5,6-tetrafluoropyridine-3-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.1%

2,3,4,6-tetrafluoropyridine (3512-13-8,63745-12-0) + carbon dioxide (124-38-9,18923-20-1) → 2,4,5,6-Tetrafluoronicotinic acid (3512-15-0)

Guidance literature:

2,3,4,6-tetrafluoropyridine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h;

carbon dioxide; In diethyl ether; hexane; at -55 ℃; for 2h;

DOI:10.1016/S0022-1139(99)00189-X

Reference yield:

→ 2,4,5,6-Tetrafluoronicotinic acid (3512-15-0)

Guidance literature:

2,4,5,6-Tetrafluorpyridin, 1. BuLi (Hexan, -60grad, N2), 2. CO2;

Reference yield: 71.9%

2,4,5,6-Tetrafluoronicotinic acid (3512-15-0) → 4-Aminotrifluoronicotinic acid (259675-74-6)

Guidance literature:

With ammonia; at 20 ℃; for 15h;

DOI:10.1016/S0022-1139(99)00189-X

upstream raw materials:

2,3,4,6-tetrafluoropyridine

carbon dioxide

Downstream raw materials:

4-Aminotrifluoronicotinic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 3512-15-0 2,4,5,6-Tetrafluoronicotinic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send