C₇₀H₇₇N₃O₁₃Si

Base Information

• Chemical Name: C₇₀H₇₇N₃O₁₃Si
• CAS No.: 133006-28-7
• Molecular Formula: C₇₀H₇₇N₃O₁₃Si
• Molecular Weight: 1196.48
• Mol file: 133006-28-7.mol

Synonyms:

Chemical Property of C₇₀H₇₇N₃O₁₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₀H₇₇N₃O₁₃Si

There total 18 articles about C₇₀H₇₇N₃O₁₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H23NO5 (132938-56-8) + 2,2,2-Trichloro-acetimidic acid (3R,4S,6R)-5-[(E)-benzyloxyimino]-3-{(2S,4S,5S)-5-[ethyl-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-4-methoxy-tetrahydro-pyran-2-yloxy}-6-methyl-4-triethylsilanyloxy-tetrahydro-pyran-2-yl ester (148152-88-9) → C70H77N3O13Si (132938-57-9) + C70H77N3O13Si (133006-27-6) + C70H77N3O13Si (133006-29-8) + C70H77N3O13Si (133006-28-7)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -60 - -40 ℃; for 1h; Yield given. Yields of byproduct given;

Reference yield:

D-Fucose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) → C70H77N3O13Si (133006-28-7)

Guidance literature:

Multi-step reaction with 13 steps

1: 98 percent / NEt₃, 4-dimethylaminopyridine / CH₂Cl₂ / 2 h / 0 - 25 °C

2: 30percent HBr, acetic acid / 0.5 h / 0 °C

3: AgCO₃ / CH₂Cl₂ / 16 h / 25 °C / 3 Angstroem-Molekularsieb

4: 95 percent / NaOMe, MeOH / 3 h / 25 °C

5: 90 percent / acetonitrile / 2 h / Heating

6: AgClO₄, SnCl₂ / tetrahydrofuran / 6 h / -90 - -10 deg C

7: 90 percent / NaH, ethanediol / tetrahydrofuran / 0.5 h / 0 °C

8: 1) n-Bu₂SnO, 2) Br₂, n-Bu₃SnOMe / 1) MeOH, 1h, reflux, 2) CH₂Cl₂, 2h, 25 deg C

9: 90 percent / pyridinium-p-toluenesulfonate / benzene / 0.5 h / 25 °C

10: 98 percent / 2,6-Lutidin / CH₂Cl₂ / 0.5 h / 0 °C

11: 95 percent / tetrahydrofuran; H₂O / 0.25 h / 0 °C / Irradiation

12: 98 percent / NaH / CH₂Cl₂ / 2 h / 25 °C

13: BF₃*OEt₂ / CH₂Cl₂ / 1 h / -60 - -40 °C

With 2,6-dimethylpyridine; methanol; dmap; silver (II) carbonate; boron trifluoride diethyl etherate; hydrogen bromide; bromine; sodium methylate; tributyltin methoxide; silver perchlorate; pyridinium p-toluenesulfonate; sodium hydride; di(n-butyl)tin oxide; ethylene glycol; acetic acid; triethylamine; tin(ll) chloride; In tetrahydrofuran; dichloromethane; water; acetonitrile; benzene;

Reference yield:

N-benzyloxyamine (622-33-3) → C70H77N3O13Si (133006-28-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / pyridinium-p-toluenesulfonate / benzene / 0.5 h / 25 °C

2: 98 percent / 2,6-Lutidin / CH₂Cl₂ / 0.5 h / 0 °C

3: 95 percent / tetrahydrofuran; H₂O / 0.25 h / 0 °C / Irradiation

4: 98 percent / NaH / CH₂Cl₂ / 2 h / 25 °C

5: BF₃*OEt₂ / CH₂Cl₂ / 1 h / -60 - -40 °C

With 2,6-dimethylpyridine; boron trifluoride diethyl etherate; pyridinium p-toluenesulfonate; sodium hydride; In tetrahydrofuran; dichloromethane; water; benzene;

upstream raw materials:

C₂₈H₂₃NO₅

2,2,2-Trichloro-acetimidic acid (3R,4S,6R)-5-[(E)-benzyloxyimino]-3-{(2S,4S,5S)-5-[ethyl-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-4-methoxy-tetrahydro-pyran-2-yloxy}-6-methyl-4-triethylsilanyloxy-tetrahydro-pyran-2-yl ester

D-Fucose

N-benzyloxyamine