Technology Process of C20H21NO3
There total 5 articles about C20H21NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C12H15NO;
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
benzyl chloroformate;
In
dichloromethane;
at 20 ℃;
for 4h;
Inert atmosphere;
DOI:10.1021/jo500249c
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sulfuric acid / dichloromethane / 24 h / 0 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
2.2: 4 h / 20 °C / Inert atmosphere
With
sulfuric acid; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
1.1: |Aza-Claisen Rearrangement;
DOI:10.1021/jo500249c
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 4 h / 100 °C
2.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / -78 °C / Inert atmosphere
3.1: tetrahydrofuran; hexane / 20 h / 20 °C / Inert atmosphere
4.1: sulfuric acid / dichloromethane / 24 h / 0 °C / Inert atmosphere
5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
5.2: 4 h / 20 °C / Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sulfuric acid; diisobutylaluminium hydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene;
4.1: |Aza-Claisen Rearrangement;
DOI:10.1021/jo500249c
