2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine

Base Information

Chemical Name:2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine
CAS No.:196504-64-0
Molecular Formula:C₃₀H₃₀N₂O₇S
Molecular Weight:562.643
Hs Code.:
DSSTox Substance ID:DTXSID501209402

Synonyms:DTXSID501209402;2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine;196504-64-0

Suppliers and Price of 2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:562.17737247
Heavy Atom Count:40
Complexity:873

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)SC4C(C(OC4N5C=CC(=O)NC5=O)CO)O
Isomeric SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)S[C@@H]4[C@@H]([C@H](O[C@H]4N5C=CC(=O)NC5=O)CO)O

Technology Process of 2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine

There total 2 articles about 2'-S-[Bis(4-methoxyphenyl)phenylmethyl]-2'-thiouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 83088-00-0
2'-deoxy-2'-(4-methoxyphenylmethanethio)uridine

: 196504-64-0
2'-S-(4,4'-Dimethoxytrityl)-2'-thiouridine

Guidance literature:: Multi-step reaction with 2 steps

1: TFA, phenol / 2 h / Heating

2: NaHCO₃ / tetrahydrofuran / 3 h / Ambient temperature

With sodium hydrogencarbonate; trifluoroacetic acid; phenol; In tetrahydrofuran;

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 31281-28-4
2'-mercapto-2'-deoxyuridine

: 196504-64-0
2'-S-(4,4'-Dimethoxytrityl)-2'-thiouridine

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; for 3h; Yield given; Ambient temperature;

Reference yield:

: 196504-64-0
2'-S-(4,4'-Dimethoxytrityl)-2'-thiouridine

: 196504-69-5
2'-S-(4,4'-Dimethoxytrityl)-2'-thiocytidine

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 18 h / Ambient temperature

2: K₂CO₃ / acetonitrile / Ambient temperature

3: NH₃ / CH₂Cl₂ / 48 h / Ambient temperature

4: conc. NH₄OH / ethanol / 24 h

With pyridine; ammonium hydroxide; ammonia; potassium carbonate; In ethanol; dichloromethane; acetonitrile;