Technology Process of 7-benzyloxy-6-hydroxy-3-methoxy-3',4'-methylenedioxyflavone
There total 4 articles about 7-benzyloxy-6-hydroxy-3-methoxy-3',4'-methylenedioxyflavone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.8 g / K2CO3, KJ / acetone / 6 h / Heating
2: 1.) pyridine, aq. KOH, aq. potassium persulphate, 2.) sodium bisulphite, conc. HCl (d = 1.18) / 2.) 60-70 deg C, 30 min.
3: 1.) sodium piperonylate, 2.) aq. KOH / 1.) 190-200 deg C oil-bath, 12 mm, 4 h, 2.) ethyl alcohol, reflux, 1 h
With
pyridine; hydrogenchloride; potassium hydroxide; potassium peroxomonosulphate; 3,4-methylenedioxybenzoic acid sodium salt; potassium carbonate; sodium hydrogensulfite;
In
acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.8 g / K2CO3, KJ / acetone / 6 h / Heating
2: 1.) pyridine, aq. KOH, aq. potassium persulphate, 2.) sodium bisulphite, conc. HCl (d = 1.18) / 2.) 60-70 deg C, 30 min.
3: 1.) sodium piperonylate, 2.) aq. KOH / 1.) 190-200 deg C oil-bath, 12 mm, 4 h, 2.) ethyl alcohol, reflux, 1 h
With
pyridine; hydrogenchloride; potassium hydroxide; potassium peroxomonosulphate; 3,4-methylenedioxybenzoic acid sodium salt; potassium carbonate; sodium hydrogensulfite;
In
acetone;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) pyridine, aq. KOH, aq. potassium persulphate, 2.) sodium bisulphite, conc. HCl (d = 1.18) / 2.) 60-70 deg C, 30 min.
2: 1.) sodium piperonylate, 2.) aq. KOH / 1.) 190-200 deg C oil-bath, 12 mm, 4 h, 2.) ethyl alcohol, reflux, 1 h
With
pyridine; hydrogenchloride; potassium hydroxide; potassium peroxomonosulphate; 3,4-methylenedioxybenzoic acid sodium salt; sodium hydrogensulfite;
