Technology Process of 6-amino-5-phenylsulfanyl-benzofuran-3-one
There total 9 articles about 6-amino-5-phenylsulfanyl-benzofuran-3-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; iron; ammonium chloride;
In
ethanol;
for 4h;
Heating;
DOI:10.1055/s-2000-6396
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: NaNO2; H2O; HBF4 / 0.5 h / 0 °C
1.2: 75 percent / Cu; NaNO2 / H2O / 3 h / 20 °C
2.1: 97 percent / HBr; AcOH; Ac2O / 6 h / Heating
3.1: 85 percent / H2SO4 / 24 h / Heating
4.1: 98 percent / K2CO3 / acetone / 12 h / Heating
5.1: 99 percent / KOH; H2O / methanol; dioxane / 18 h / 20 °C
6.1: 71 percent / AcONa; AcOH / 4 h / Heating
7.1: 85 percent / HCl; H2O / 6 h / Heating
8.1: 67 percent / t-BuOK / 2-methyl-propan-2-ol / 72 h / Heating
9.1: Fe; NH4Cl; H2O / ethanol / 4 h / Heating
With
hydrogenchloride; potassium hydroxide; tetrafluoroboric acid; sulfuric acid; potassium tert-butylate; water; hydrogen bromide; sodium acetate; acetic anhydride; iron; potassium carbonate; ammonium chloride; acetic acid; sodium nitrite;
In
1,4-dioxane; methanol; ethanol; acetone; tert-butyl alcohol;
1.1: Diazotization / 1.2: Substitution / 2.1: ether cleavage / 3.1: Esterification / 4.1: Alkylation / 5.1: Hydrolysis / 6.1: Cyclization / 7.1: methanolysis / 8.1: Substitution / 9.1: Reduction;
DOI:10.1055/s-2000-6396
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 67 percent / t-BuOK / 2-methyl-propan-2-ol / 72 h / Heating
2: Fe; NH4Cl; H2O / ethanol / 4 h / Heating
With
potassium tert-butylate; water; iron; ammonium chloride;
In
ethanol; tert-butyl alcohol;
1: Substitution / 2: Reduction;
DOI:10.1055/s-2000-6396
