4-Amino-5-bromo-2-methoxybenzoic acid

Base Information

Chemical Name:4-Amino-5-bromo-2-methoxybenzoic acid
CAS No.:35290-97-2
Molecular Formula:C8H8BrNO3
Molecular Weight:246.06
Hs Code.:2922509090
European Community (EC) Number:252-491-8
UNII:SVJ2V07DZM
DSSTox Substance ID:DTXSID70188783
Nikkaji Number:J260.572D
Wikidata:Q83060628
ChEMBL ID:CHEMBL1705592
Mol file:35290-97-2.mol

Synonyms:4-Amino-5-bromo-2-methoxybenzoic acid;35290-97-2;4-amino-5-bromo-2-methoxybenzenecarboxylic acid;Benzoic acid, 4-amino-5-bromo-2-methoxy-;SVJ2V07DZM;EINECS 252-491-8;2-Methoxy-4-amino-5-bromobenzoic acid;4-AMINO-5-BROMO-2-METHOXYBENZENECARBOXYLICACID;5-Bromo-4-amino-2-methoxybenzoic acid;UNII-SVJ2V07DZM;Oprea1_168799;MLS000755304;SCHEMBL866041;CHEMBL1705592;DTXSID70188783;HMS2634O11;HMS3360I04;MFCD02186027;4-Amino-5-bromo-2-methoxybenzoicacid;AKOS005070022;4-AMINO-5-BROMO-O-ANISIC ACID;2-methoxy-4-amino-5-bromo benzoic acid;4-amino-5-bromo-2-methoxy-benzoic acid;NCGC00246541-01;SMR000338181;4-Amino-5-bromo-2-methoxybenzoic acid #;FT-0680220;2R-0683;J-514387;4-amino-5-bromo-2-methoxybenzenecarboxylic acid, AldrichCPR

Suppliers and Price of 4-Amino-5-bromo-2-methoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Amino-5-bromo-2-methoxybenzenecarboxylicAcid
100mg
$ 160.00

TRC
4-Amino-5-bromo-2-methoxybenzenecarboxylicAcid
1g
$ 1260.00

Matrix Scientific
4-Amino-5-bromo-2-methoxybenzenecarboxylic acid >95%
500mg
$ 365.00

Matrix Scientific
4-Amino-5-bromo-2-methoxybenzenecarboxylic acid >95%
1g
$ 550.00

Matrix Scientific
4-Amino-5-bromo-2-methoxybenzenecarboxylic acid >95%
5g
$ 1200.00

Crysdot
4-Amino-5-bromo-2-methoxybenzoicacid 97%
5g
$ 886.00

Chemcia Scientific
4-Amino-5-bromo-2-methoxy-benzoicacid ＞97%
5 G
$ 645.00

Chemcia Scientific
4-Amino-5-bromo-2-methoxy-benzoicacid ＞97%
10 G
$ 995.00

American Custom Chemicals Corporation
4-AMINO-5-BROMO-2-METHOXYBENZENECARBOXYLIC ACID 95.00%
1G
$ 414.75

Alichem
4-Amino-5-bromo-2-methoxybenzoicacid
5g
$ 922.88

Total 28 raw suppliers

Chemical Property of 4-Amino-5-bromo-2-methoxybenzoic acid

Chemical Property:

Vapor Pressure:5.77E-07mmHg at 25°C
Melting Point:186-188°C
Refractive Index:1.636
Boiling Point:395.5 °C at 760 mmHg
PKA:4.36±0.10(Predicted)
Flash Point:193 °C
PSA：72.55000
Density:1.703 g/cm³
LogP:2.31930
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:244.96876
Heavy Atom Count:13
Complexity:200

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-5-bromo-2-methoxybenzenecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1C(=O)O)Br)N
Uses 4-Amino-5-bromo-2-methoxybenzenecarboxylic acid is an impurity of bromopride (B686645), which is an antiemetic.

Technology Process of 4-Amino-5-bromo-2-methoxybenzoic acid

There total 8 articles about 4-Amino-5-bromo-2-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 4093-34-9
2-Methoxy-4-cetamino-5-brom-benzoesaeuremethylester

: 35290-97-2
4-amino 5-bromo 2-methoxy benzoic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 70 ℃;

Reference yield: 70.0%

: 111049-68-4
methyl 4-amino-5-bromo-2-methoxybenzenecarboxylate

: 35290-97-2
4-amino 5-bromo 2-methoxy benzoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; methanol; at 50 ℃; for 2h;
DOI:10.1021/jm100060b

Reference yield:

: 4093-29-2
methyl 4-(acetylamino)-o-anisate

: 35290-97-2
4-amino 5-bromo 2-methoxy benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide

2: sodium hydroxide / ethanol

With N-Bromosuccinimide; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/157018012800389386