(2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate

Base Information

• Chemical Name: (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate
• CAS No.: 107686-51-1
• Molecular Formula: C₂₅H₂₅Cl₂F₃O₄
• Molecular Weight: 517.372
• Mol file: 107686-51-1.mol

Synonyms:

Chemical Property of (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate

There total 3 articles about (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic anhydride (108-24-7) + (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(2,2-dichloro-3,3,3-trifluoro-1-hydroxypropyl)-2,2-dimethylcyclopropanecarboxylate (107686-48-6,107794-45-6,110171-52-3) → (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate (107686-51-1,107794-49-0,110171-55-6)

Guidance literature:

With pyridine;

DOI:10.1016/S0040-4039(00)84469-X

Reference yield:

(2-methyl[1,1'-biphenyl]-3-yl)methyl cis,trans-2,2-dimethyl-3-formylcyclopropanecarboxylate (107489-30-5) → (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate (107686-51-1,107794-49-0,110171-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc / dimethylformamide / 0 deg C, 2 h; 50 deg C, 10 h

2: 100 percent / pyridine / 5 h / Ambient temperature

With zinc; In pyridine; N,N-dimethyl-formamide;

DOI:10.1246/bcsj.60.4385

Reference yield:

(2-methyl-3-phenylphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate (107686-57-7) → (2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(1-acetoxy-2,2-dichloro-3,3,3-trifluoropropyl)-2,2-dimethylcyclopropanecarboxylate (107686-51-1,107794-49-0,110171-55-6)

Guidance literature:

Multi-step reaction with 3 steps

1: O₃

2: 86 percent / Zn / dimethylformamide

3: 100 percent / pyridine

With pyridine; ozone; zinc; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)84469-X

upstream raw materials:

acetic anhydride

(2-methyl-3-phenylphenyl)methyl (1RS,3SR)-3-(2,2-dichloro-3,3,3-trifluoro-1-hydroxypropyl)-2,2-dimethylcyclopropanecarboxylate

(2-methyl[1,1'-biphenyl]-3-yl)methyl cis,trans-2,2-dimethyl-3-formylcyclopropanecarboxylate

(2-methyl-3-phenylphenyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate

Downstream raw materials:

(2-methyl-3-phenylphenyl)methyl (Z)-(1RS,3SR)-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate

(2-methyl-3-phenylphenyl)methyl (E)-(1RS,3SR)-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate

(1R,3S)-3-((Z)-2-Chloro-3,3,3-trifluoro-propenyl)-2,2-dimethyl-cyclopropanecarboxylic acid 2-methyl-biphenyl-3-ylmethyl ester