ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate

Base Information

• Chemical Name: ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate
• CAS No.: 1163128-81-1
• Molecular Formula: C₂₀H₃₅ClNO₅PS
• Molecular Weight: 467.994
• Mol file: 1163128-81-1.mol

Synonyms:

Chemical Property of ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate

There total 1 articles about ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

(S)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide (1207946-36-8) + 1-[1-ethoxy-1-(ethoxy(methyl)phosphoryl)ethoxy]ethane (75174-69-5) → ethyl 1',1'-diethoxyethyl-(S(S),R(C),S(P))-(+)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate (1163128-80-0) + ethyl 1',1'-diethoxyethyl-(S(S),R(C),R(P))-(-)-2-(tert-butylsulfinylamino)-2-(para-chlorophenyl)ethylphosphinate (1163128-81-1)

Guidance literature:

1-[1-ethoxy-1-(ethoxy(methyl)phosphoryl)ethoxy]ethane; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

(S)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide; In tetrahydrofuran; at -78 ℃; for 12h; stereoselective reaction; Inert atmosphere;

DOI:10.1002/chem.200802248

upstream raw materials:

(S)-N-(4-chlorobenzylidene)-2-methylpropane-2-sulfinamide

1-[1-ethoxy-1-(ethoxy(methyl)phosphoryl)ethoxy]ethane