Technology Process of C9H9(2)HN2O4
There total 7 articles about C9H9(2)HN2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium aluminium deuteride / diethylene glycol dimethyl ether; tert-butyl alcohol / 0.5 h / -78 °C
2: piperidine / pyridine / 80 °C
3: ammonium hydroxide / 18 h / 30 °C / pH 9.5 / Enzymatic reaction
With
piperidine; ammonium hydroxide; lithium aluminium deuteride;
In
pyridine; diethylene glycol dimethyl ether; tert-butyl alcohol;
DOI:10.1002/anie.201311061
- Guidance literature:
-
Multi-step reaction with 2 steps
1: piperidine / pyridine / 80 °C
2: ammonium hydroxide / 18 h / 30 °C / pH 9.5 / Enzymatic reaction
With
piperidine; ammonium hydroxide;
In
pyridine;
DOI:10.1002/anie.201311061
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydrogen; (-)-1,2-bis-[(2R,5R)-2,5-diethylphospholano]benzene(cyclooctadiene)rhodium(I) tetrafluoroborate / methanol / 1.5 h / 5171.62 Torr
2: hydrogenchloride / water; acetone / 7 h / Reflux
3: E. coli BL21(DE3) whole cells expressing Anabaena variabilis phenylalanine ammonia lyase / aq. buffer / 48 h / 30 °C / pH 8.3 / Enzymatic reaction
4: ammonium hydroxide / 18 h / 30 °C / pH 9.5 / Enzymatic reaction
With
hydrogenchloride; ammonium hydroxide; (-)-1,2-bis-[(2R,5R)-2,5-diethylphospholano]benzene(cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen;
In
methanol; water; acetone;
DOI:10.1002/anie.201311061
