1,3-dipropyl-8-xanthine

Base Information

Chemical Name:1,3-dipropyl-8-xanthine
CAS No.:127946-10-5
Molecular Formula:C₁₈H₂₉N₅O₂
Molecular Weight:347.461
Hs Code.:

1,3-dipropyl-8-<trans-4-(aminomethyl)cyclohexyl>xanthine

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-dipropyl-8-xanthine

Chemical Property:

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Technology Process of 1,3-dipropyl-8-xanthine

There total 4 articles about 1,3-dipropyl-8-xanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[(2,2,2-Trifluoro-acetylamino)-methyl]-cyclohexanecarboxylic acid (6-amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-amide

: 127946-10-5
1,3-dipropyl-8-xanthine

Guidance literature:: With sodium hydroxide; at 90 ℃; for 1h;
DOI:10.1021/jm00169a012

Reference yield:

: 81250-34-2
1,3-dipropyl-5,6-diaminouracil

: 127946-10-5
1,3-dipropyl-8-xanthine

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / H₂O / Ambient temperature

2: 2.5 M aq. NaOH / 1 h / 90 °C

With sodium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water;
DOI:10.1021/jm00169a012

Reference yield:

: 1197-18-8
trans-4-aminomethyl-cyclohexyl-carboxylic acid

: 127946-10-5
1,3-dipropyl-8-xanthine

Guidance literature:: Multi-step reaction with 3 steps

1: 65.6 percent / CH₂Cl₂ / 24 h / Ambient temperature

2: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / H₂O / Ambient temperature

3: 2.5 M aq. NaOH / 1 h / 90 °C

With sodium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; water;
DOI:10.1021/jm00169a012