Technology Process of Ethyl 2-Iodomethyl-4,6-dimethoxy-3-methylphenyl Ketone
There total 5 articles about Ethyl 2-Iodomethyl-4,6-dimethoxy-3-methylphenyl Ketone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) NaNH2, 2.) 20percent HCl / 1.) THF, reflux, 18 h, 2.) THF, RT, 16 h
2: 89 percent / diethyl ether / 10 h / 0 °C
3: benzene / Irradiation
With
hydrogenchloride; sodium amide;
In
diethyl ether; benzene;
DOI:10.1246/bcsj.63.2435
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 50 percent / Zn, HgCl2, concd. HCl / toluene / 2 h / Heating
2: 1.) NaNH2, 2.) 20percent HCl / 1.) THF, reflux, 18 h, 2.) THF, RT, 16 h
3: 89 percent / diethyl ether / 10 h / 0 °C
4: benzene / Irradiation
With
hydrogenchloride; sodium amide; mercury dichloride; zinc;
In
diethyl ether; toluene; benzene;
DOI:10.1246/bcsj.63.2435
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 81 percent / Br2 / CCl4 / 1.) 40 min, 0 Deg C, 2.) 1 h, RT
2: 50 percent / Zn, HgCl2, concd. HCl / toluene / 2 h / Heating
3: 1.) NaNH2, 2.) 20percent HCl / 1.) THF, reflux, 18 h, 2.) THF, RT, 16 h
4: 89 percent / diethyl ether / 10 h / 0 °C
5: benzene / Irradiation
With
hydrogenchloride; bromine; sodium amide; mercury dichloride; zinc;
In
tetrachloromethane; diethyl ether; toluene; benzene;
DOI:10.1246/bcsj.63.2435
