(2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran

Base Information

• Chemical Name: (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran
• CAS No.: 182187-81-1
• Molecular Formula: C₄₃H₅₆O₆Si₂
• Molecular Weight: 725.085
• Mol file: 182187-81-1.mol

Synonyms:

Chemical Property of (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran

There total 2 articles about (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-3,5-diol (182187-85-5) + methyl trifluoromethanesulfonate (333-27-7) → (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran (182187-81-1)

Guidance literature:

With 2,6-di-tert-butyl-pyridine; In dichloromethane; at 80 ℃; for 24h;

DOI:10.1016/0040-4020(96)00600-X

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → (2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,5-dimethoxy-tetrahydro-pyran (182187-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: imidazole / dimethylformamide / 8 h / 20 °C

2: 68 percent Spectr_. / 2,6-di-tert-butylpyridine / CH₂Cl₂ / 24 h / 80 °C

With 1H-imidazole; 2,6-di-tert-butyl-pyridine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/0040-4020(96)00600-X

upstream raw materials:

(2S,3S,4S,5R,6R)-2-Allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-3,5-diol

methyl trifluoromethanesulfonate

tert-butylchlorodiphenylsilane