acetoxyacetic acid

Base Information

• Chemical Name: acetoxyacetic acid
• CAS No.: 142991-91-1
• Molecular Formula: C₁₄H₂₁NO₆
• Molecular Weight: 299.324
• Mol file: 142991-91-1.mol

Synonyms:

Chemical Property of acetoxyacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetoxyacetic acid

There total 6 articles about acetoxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetic anhydride (108-24-7) + (hydroxy)acetic acid (158213-00-4) → acetoxyacetic acid (142991-91-1,142991-92-2)

Guidance literature:

With pyridine; dmap;

DOI:10.1016/S0040-4020(01)81240-0

Reference yield:

cyclohex-3-enylmethanol (72581-32-9,1679-51-2) → acetoxyacetic acid (142991-91-1,142991-92-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 100 percent / Et₃N / CH₂Cl₂

2: 98 percent / NaN₃ / dimethylformamide

3: 73 percent / PPh₃, H₂O / tetrahydrofuran

4: 97 percent / Et₃N / CH₂Cl₂

5: 59 percent / benzene

6: 90 percent / pyridine, DMAP

With pyridine; dmap; sodium azide; water; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4020(01)81240-0

Reference yield:

(3-cyclohexen-1-yl)methylamine (2555-10-4) → acetoxyacetic acid (142991-91-1,142991-92-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / Et₃N / CH₂Cl₂

2: 59 percent / benzene

3: 90 percent / pyridine, DMAP

With pyridine; dmap; triethylamine; In dichloromethane; benzene;

DOI:10.1016/S0040-4020(01)81240-0

upstream raw materials:

acetic anhydride

(hydroxy)acetic acid

cyclohex-3-enylmethanol

(3-cyclohexen-1-yl)methylamine

Downstream raw materials:

N-(2-(1-cyclohexen-1-yl)ethyl)-N-(methoxycarbonyl)glycine methyl ester

(phenylthio)acetic acid methyl ester