2555-10-4

Upstream product

• 100-45-8 3-cyclohexene-1-carbonitrile 
• 104023-30-5 4-(azidomethyl)-1-cyclohexene 
• 64-17-5 ethanol 
• 31865-09-5 4-chloro-cyclohex-3-enecarbonitrile 
• 100-50-5 3-Cyclohexene-1-carboxaldehyde 
• 57606-87-8 3-cyclohexene-1-carboxaldehyde oxime 
• 92864-78-3 cyclohex-3-en-1-ylmethyl 4-methylbenzenesulfonate 
• 108541-48-6 [(cyclohex-3-en-1-yl)methyl]methanesulfonate 
• 72581-32-9 cyclohex-3-enylmethanol 
• 24480-81-7 3,4-Dichloro-cyclohex-3-enecarbonitrile 
• 2555-08-0 4-(chloromethyl)cyclohex-1-ene 

Downstream Products

• 32591-39-2 4-cyclohex-3-enylmethyl-morpholine 
• 32591-36-9 ethyl (cyclohex-3-enylmethyl)carbamate 
• 1018480-56-2 C₁₉H₂₀F₃N₃O₂S 
• 1423074-47-8 (1R,5S)-3-methyl-7-(pyridin-3-yl)-3-azabicyclo[3.3.1]non-6-ene p-hydroxybenzoate 
• 142991-91-1 acetoxyacetic acid 
• 158213-00-4 (hydroxy)acetic acid 
• 128892-12-6 (phenylthio)acetic acid methyl ester 
• 128911-32-0 N-(2-(1-cyclohexen-1-yl)ethyl)-N-(methoxycarbonyl)glycine methyl ester 
• 32591-23-4 methyl N-<(3-cyclohexen-1-yl)methyl>carbamate 

Relevant academic research and scientific papers

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.

Development of a scalable synthesis of a pyridinyl-3-azabicyclononene, a novel nicotinic partial agonist

The process research and development of two syntheses of a novel nicotinic partial agonist, TC-8817 ((+)-5), are described. The original Medicinal Chemistry route had multiple flaws, making it unsuitable for further development. A second approach was expl

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas (1 or 2), as described herein. The compounds of Formulas (1 and 2) are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.

Reductive Cyclization of Carbon-Centered Glycine Radicals; A Novel Synthetic Route to Cyclic α-Amino Acids

Reductive cyclizations (tributyltin hydride, AIBN) of several α-(phenylthio)glycine derivatives with a 3-alkenyl substituent at nitrogen are reported.These reactions proceed via 2-aza-5-alken-1-yl radicals as intermediates which bear electron-withdrawing

Reduction d'azides par la triphenylphosphine en presence d'eau : une methode generale et chimioselective d'acces aux amines primaires

The reaction of azides with one equivalent of triphenylphosphine in the presence of a slight excess of water in THF leads quantitatively to the corresponding primary amines.This transformation is chemoselective.