Technology Process of (2S,3S)-3-amino-2-benzyl-3-phenylpropionic acid hydrochloride
There total 7 articles about (2S,3S)-3-amino-2-benzyl-3-phenylpropionic acid hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; trifluoroacetic acid;
for 24h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 74 percent / conc. H2SO4 / CH2Cl2 / 24 h
2: 45 percent / 2.) 2,6-di-tert-butylphenol / 1.) toluene, -78 - -30 deg C, 3 h, 2.) THF, RT
3: 57 percent / hydrogen / Pd/C
4: 98 percent / trifluoroacetic acid, HCl / 24 h / Ambient temperature
With
hydrogenchloride; 2,6-di-tert-butylphenol; sulfuric acid; hydrogen; trifluoroacetic acid;
palladium on activated charcoal;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 14 percent / acetic anhydride / 48 h / 120 °C
2: 74 percent / conc. H2SO4 / CH2Cl2 / 24 h
3: 45 percent / 2.) 2,6-di-tert-butylphenol / 1.) toluene, -78 - -30 deg C, 3 h, 2.) THF, RT
4: 57 percent / hydrogen / Pd/C
5: 98 percent / trifluoroacetic acid, HCl / 24 h / Ambient temperature
With
hydrogenchloride; 2,6-di-tert-butylphenol; sulfuric acid; hydrogen; acetic anhydride; trifluoroacetic acid;
palladium on activated charcoal;
In
dichloromethane;
