8-acetylthio pentafluorophenyl octanoate

Base Information

• Chemical Name: 8-acetylthio pentafluorophenyl octanoate
• CAS No.: 1021180-29-9
• Molecular Formula: C₁₆H₁₇F₅O₃S
• Molecular Weight: 384.367
• Mol file: 1021180-29-9.mol

Synonyms:

Chemical Property of 8-acetylthio pentafluorophenyl octanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-acetylthio pentafluorophenyl octanoate

There total 3 articles about 8-acetylthio pentafluorophenyl octanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2,3,4,5,6-pentafluorophenol (771-61-9) + 8-(thioacetyl)-octanoic acid → 8-acetylthio pentafluorophenyl octanoate (1021180-29-9)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 12h; Inert atmosphere;

DOI:10.1021/ja411969e

Reference yield: 39.0%

2,3,4,5,6-pentafluorophenol (771-61-9) + 8-acetylsulfanyloctanoic acid → 8-acetylthio pentafluorophenyl octanoate (1021180-29-9)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 12h; Inert atmosphere;

DOI:10.1021/ja211030y

Reference yield:

8-bromooctanoic acid (17696-11-6) → 8-acetylthio pentafluorophenyl octanoate (1021180-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 48 h / Reflux

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; acetone;

DOI:10.1021/ja211030y

upstream raw materials:

8-bromooctanoic acid

2,3,4,5,6-pentafluorophenol