C₄₉H₅₆O₉

Base Information

• Chemical Name: C₄₉H₅₆O₉
• CAS No.: 115031-01-1
• Molecular Formula: C₄₉H₅₆O₉
• Molecular Weight: 788.978
• Mol file: 115031-01-1.mol

Synonyms:

Chemical Property of C₄₉H₅₆O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₅₆O₉

There total 11 articles about C₄₉H₅₆O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) → C49H56O9 (115031-01-1,115075-73-5)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridinium tosylate / benzene / 2 h / 80 °C

2: !) nBuLi; 2) PhSeCl; 3) 3-chloroperoxybenzoic acid, aq. NaHCO₃ / 1) THF, -78 deg C, 30 min; 2) THF, -78 deg C, 15 min; 3) THF, 10 deg C, 20 min

3: 1) tBuLi; 3) Na-Hg, Na₂HPO₄ / 1) THF, -78 deg C, 20 min; 2) THF, -78 deg C to room temp.; 3) MeOH, THF, -30 deg C, 30 min

4: TBAF / tetrahydrofuran / 2 h / 65 °C

5: 1) (COCl)2, DMSO, 2) Et₃N / 1) -60 deg C, 20 min, 2) -60 deg C to room temp., 1h

With disodium hydrogenphosphate; sodium amalgam; oxalyl dichloride; tetrabutyl ammonium fluoride; tert.-butyl lithium; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; benzene;

DOI:10.1016/S0040-4039(00)96835-7

Reference yield:

(+)-(1S,3S,4S,6S)-6-<(tert-butyldiphenylsilyloxy)methyl>-4-methyl-1-<1-methylene-3-(phenylsulphonyl)propyl>-1,3-cyclohexanediol (115075-76-8) → C49H56O9 (115031-01-1,115075-73-5)

Guidance literature:

Multi-step reaction with 6 steps

1: 1) BH₃*Me₂S; 2) NaOH, aq. H₂O₂ / 1) THF, -20 deg C, 16 h; 2) H₂O, room temp., 30 min

2: pyridinium tosylate / benzene / 2 h / 80 °C

3: !) nBuLi; 2) PhSeCl; 3) 3-chloroperoxybenzoic acid, aq. NaHCO₃ / 1) THF, -78 deg C, 30 min; 2) THF, -78 deg C, 15 min; 3) THF, 10 deg C, 20 min

4: 1) tBuLi; 3) Na-Hg, Na₂HPO₄ / 1) THF, -78 deg C, 20 min; 2) THF, -78 deg C to room temp.; 3) MeOH, THF, -30 deg C, 30 min

5: TBAF / tetrahydrofuran / 2 h / 65 °C

6: 1) (COCl)2, DMSO, 2) Et₃N / 1) -60 deg C, 20 min, 2) -60 deg C to room temp., 1h

With sodium hydroxide; disodium hydrogenphosphate; sodium amalgam; oxalyl dichloride; dimethylsulfide borane complex; tetrabutyl ammonium fluoride; dihydrogen peroxide; tert.-butyl lithium; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; benzene;

DOI:10.1016/S0040-4039(00)96835-7

Reference yield:

(1R,3S,4S,6S)-1-((S)-3-Benzenesulfonyl-1-hydroxymethyl-propyl)-6-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-cyclohexane-1,3-diol (115030-95-0,115075-71-3,127854-64-2,127854-65-3) → C49H56O9 (115031-01-1,115075-73-5)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridinium tosylate / benzene / 2 h / 80 °C

2: !) nBuLi; 2) PhSeCl; 3) 3-chloroperoxybenzoic acid, aq. NaHCO₃ / 1) THF, -78 deg C, 30 min; 2) THF, -78 deg C, 15 min; 3) THF, 10 deg C, 20 min

3: 1) tBuLi; 3) Na-Hg, Na₂HPO₄ / 1) THF, -78 deg C, 20 min; 2) THF, -78 deg C to room temp.; 3) MeOH, THF, -30 deg C, 30 min

4: TBAF / tetrahydrofuran / 2 h / 65 °C

5: 1) (COCl)2, DMSO, 2) Et₃N / 1) -60 deg C, 20 min, 2) -60 deg C to room temp., 1h

With disodium hydrogenphosphate; sodium amalgam; oxalyl dichloride; tetrabutyl ammonium fluoride; tert.-butyl lithium; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; benzene;

DOI:10.1016/S0040-4039(00)96835-7

upstream raw materials:

C₄₉H₅₈O₉

1,4-Pentadiene

Benzoic acid 2-((E)-3-methyl-6-oxo-hex-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester

(2R,5S,6S,8S,9S,11S)-5-((E)-2-Benzenesulfonyl-vinyl)-11-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-2-phenyl-1,3-dioxa-spiro[5.5]undecan-8-ol

Downstream raw materials:

(2S,6R,7S,9R,10R)-10-Benzoyloxy-5-[(2E,6E)-8-(4-benzoyloxy-1,7-dioxa-spiro[5.5]undec-2-yl)-6-methyl-octa-2,6-dien-(E)-ylidene]-9-methyl-2-phenyl-1,3-dioxa-spiro[5.5]undecane-7-carboxylic acid

C₃₅H₄₆O₇

C₃₅H₄₆O₇