2-Aminoadamantane-2-carboxylic acid

Base Information

Chemical Name:2-Aminoadamantane-2-carboxylic acid
CAS No.:42381-05-5
Molecular Formula:C11H17NO2
Molecular Weight:195.261
Hs Code.:2922499990
NSC Number:145160
UNII:F52G3FRR68
DSSTox Substance ID:DTXSID00195187
Nikkaji Number:J3.383.109I
Mol file:42381-05-5.mol

Synonyms:adamantanine;adamantanine hydrochloride

Suppliers and Price of 2-Aminoadamantane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Adamantanine
500mg
$ 495.00

SynQuest Laboratories
2-Aminoadamantane-2-carboxylic acid
1 g
$ 856.00

SynQuest Laboratories
2-Aminoadamantane-2-carboxylic acid
250 mg
$ 344.00

Matrix Scientific
2-Aminoadamantane-2-carboxylic acid
250mg
$ 284.00

Matrix Scientific
2-Aminoadamantane-2-carboxylic acid
500mg
$ 455.00

Matrix Scientific
2-Aminoadamantane-2-carboxylic acid
1g
$ 700.00

Crysdot
2-Aminoadamantane-2-carboxylicacid 95+%
1g
$ 459.00

Chemenu
2-Aminoadamantane-2-carboxylicacid 95%
1g
$ 434.00

Azepine
2-Aminoadamantane-2-carboxylicacid 95
100 mg
$ 290.00

Apolloscientific
2-Aminoadamantane-2-carboxylicacid
250mg
$ 312.00

Total 51 raw suppliers

Chemical Property of 2-Aminoadamantane-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.03E-05mmHg at 25°C
Refractive Index:1.57
Boiling Point:346.2 °C at 760 mmHg
PKA:2.49±0.20(Predicted)
Flash Point:163.2 °C
PSA：63.32000
Density:1.238 g/cm³
LogP:1.92490
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:195.125928785
Heavy Atom Count:14
Complexity:259

Purity/Quality:

99%, ^*data from raw suppliers

Adamantanine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:

Useful:

Canonical SMILES:C1C2CC3CC1CC(C2)C3(C(=O)O)N
Uses Adamantanine is a γ-turn inducer for peptides. A potential cholecystokinin-B (CCK-B) receptor selective ligands. Also, it inhibits the transport of L-leucine and L-methionine into Ehrlich ascites cells.

Technology Process of 2-Aminoadamantane-2-carboxylic acid

There total 3 articles about 2-Aminoadamantane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50346-47-9
spiro[adamantane-2,4'-imidazolidine]-2',5'-dione

: 42381-05-5
2-amino-2-adamantanecarboxylic acid

Guidance literature:: With sodium hydroxide; at 195 ℃; for 2h; under 12929 Torr;
DOI:10.1016/j.bmc.2013.04.075

Reference yield:

: 700-58-3
2-Adamantanone

: 42381-05-5
2-amino-2-adamantanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium carbonate / ethanol; water / 2 h / 20 - 150 °C / Inert atmosphere; Microwave irradiation

2: sodium hydroxide / 2 h / 195 °C / 12929 Torr

With ammonium carbonate; sodium hydroxide; In ethanol; water;
DOI:10.1016/j.bmc.2013.04.075