C₆₉H₈₁N₁₁O₁₃Si

Base Information

• Chemical Name: C₆₉H₈₁N₁₁O₁₃Si
• CAS No.: 198703-78-5
• Molecular Formula: C₆₉H₈₁N₁₁O₁₃Si
• Molecular Weight: 1300.55
• Mol file: 198703-78-5.mol

Synonyms:

Chemical Property of C₆₉H₈₁N₁₁O₁₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₉H₈₁N₁₁O₁₃Si

There total 1 articles about C₆₉H₈₁N₁₁O₁₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(9-{(2R,3R,4R,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-3-methoxy-5-[(N-methyl-aminooxy)-methyl]-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide (198703-65-0) + N-(9-{(2R,3R,4R,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-formyl-3-methoxy-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide (198703-58-1) → C69H81N11O13Si (198703-78-5)

Guidance literature:

With borane pyridine; pyridinium p-toluenesulfonate; In methanol;

DOI:10.1080/07328319708006118

Reference yield:

C69H81N11O13Si (198703-78-5) → C53H63N11O13 (198703-93-4)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran;

DOI:10.1080/07328319708006118

Reference yield:

C69H81N11O13Si (198703-78-5) → C62H80N13O14P

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N*2HF / tetrahydrofuran

2: 1.) Et₃N*3HF, Et₃N, 2.) DIPEA / 1.) THF, 2.) DCM

With triethylamine tris(hydrogen fluoride); triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;

DOI:10.1080/07328319708006118

upstream raw materials:

N-(9-{(2R,3R,4R,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-3-methoxy-5-[(N-methyl-aminooxy)-methyl]-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide

N-(9-{(2R,3R,4R,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-formyl-3-methoxy-tetrahydro-furan-2-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide

Downstream raw materials:

C₅₃H₆₃N₁₁O₁₃