2,2'-(5-bromo-1,3-phenylene)bisimidazole

Base Information

• Chemical Name: 2,2'-(5-bromo-1,3-phenylene)bisimidazole
• CAS No.: 160892-05-7
• Molecular Formula: C₁₂H₉BrN₄
• Molecular Weight: 289.134
• Mol file: 160892-05-7.mol

Synonyms:

Chemical Property of 2,2'-(5-bromo-1,3-phenylene)bisimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-(5-bromo-1,3-phenylene)bisimidazole

There total 5 articles about 2,2'-(5-bromo-1,3-phenylene)bisimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromoisophthalic acid (23351-91-9) → 2,2'-(5-bromo-1,3-phenylene)bisimidazole (160892-05-7)

Guidance literature:

Multi-step reaction with 5 steps

1: thionyl chloride / toluene; dimethylformamide / 3.5 h / Heating

2: concd. ammonium hydroxide / 1.) 0 deg C, 10 min, 2.) RT, 1h

3: 85 percent / polyphosphate ester / CHCl₃ / 16 h / Heating

4: 79 percent / sulfur / 12 h / Heating

5: 1.) oxalyl chloride, dimethyl sulfoxide, 2.) triethylamine / 1.) CH₂Cl₂, -78 deg C, 10 min, 2.) CH₂Cl₂, RT, 16 h

With ammonium hydroxide; thionyl chloride; polyphosphate ester; oxalyl dichloride; sulfur; dimethyl sulfoxide; triethylamine; In chloroform; N,N-dimethyl-formamide; toluene;

Reference yield:

5-bromobenzene-1,3-dicarboxylic acid chloride (57863-69-1) → 2,2'-(5-bromo-1,3-phenylene)bisimidazole (160892-05-7)

Guidance literature:

Multi-step reaction with 4 steps

1: concd. ammonium hydroxide / 1.) 0 deg C, 10 min, 2.) RT, 1h

2: 85 percent / polyphosphate ester / CHCl₃ / 16 h / Heating

3: 79 percent / sulfur / 12 h / Heating

4: 1.) oxalyl chloride, dimethyl sulfoxide, 2.) triethylamine / 1.) CH₂Cl₂, -78 deg C, 10 min, 2.) CH₂Cl₂, RT, 16 h

With ammonium hydroxide; polyphosphate ester; oxalyl dichloride; sulfur; dimethyl sulfoxide; triethylamine; In chloroform;

Reference yield:

5-bromo-1,3-benzenedicarboxamide (160892-06-8) → 2,2'-(5-bromo-1,3-phenylene)bisimidazole (160892-05-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / polyphosphate ester / CHCl₃ / 16 h / Heating

2: 79 percent / sulfur / 12 h / Heating

3: 1.) oxalyl chloride, dimethyl sulfoxide, 2.) triethylamine / 1.) CH₂Cl₂, -78 deg C, 10 min, 2.) CH₂Cl₂, RT, 16 h

With polyphosphate ester; oxalyl dichloride; sulfur; dimethyl sulfoxide; triethylamine; In chloroform;

upstream raw materials:

2,2'-(5-bromo-1,3-phenylene)bis<4,5-dihydroimidazole>

5-bromoisophthalic acid

5-bromobenzene-1,3-dicarboxylic acid chloride

5-bromo-1,3-benzenedicarbonitrile