23351-91-9

Basic information

• Product Name: 5-BROMOISOPHTHALIC ACID
• Synonyms: 5-BROMOISOPHTHALIC ACID;5-BROMO-1,3-BENZENEDICARBOXYLIC ACID;5-BROMOISOPHTHALIC ACID 96%;5-Bromoisophthalic acid,96%;5-Bromobenzene-1,3-dicarboxylic acid;5-Bromo-1,3-benzenedicarboxyic acid;1,3-Benzenedicarboxylic acid, 5-bromo-;1,3-Benzenedicarbo
• CAS NO: 23351-91-9
• Molecular Formula: C₈H₅BrO₄
• Molecular Weight: 245.03
• EINECS: 245-602-6
• Mol File: 23351-91-9.mol
• Article Data: 20

Chemical Properties

• Melting Point: 276-287 °C
• Boiling Point: 452.1 °C at 760 mmHg
• Flash Point: 227.2 °C
• Appearance: /
• Density: 1.875
• Vapor Pressure: 5.8E-09mmHg at 25°C
• Storage Temp.: Room temperature.
• PKA: 3.14±0.10(Predicted)
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 5-BROMOISOPHTHALIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMOISOPHTHALIC ACID(23351-91-9)
• EPA Substance Registry System: 5-BROMOISOPHTHALIC ACID(23351-91-9)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38-25
• Safety Statements: 37/39-26-45-36/37/39
• RIDADR: 2811
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 23351-91-9(Hazardous Substances Data)

Usage

Chemical Properties

white to almost white powder

Uses

Different sources of media describe the Uses of 23351-91-9 differently. You can refer to the following data:
1. Functionalizable MOF linker with an electron rich hetero atom. Reactant for: Preparation of manganese(II) bromoisophthalate bis(pyridyl)ethane coordination polymer Preparation of nickel(II) and cobalt(II) bromoisophthalate coordination polymers Preparati
2. Reactant for:Preparation of manganese(II) bromoisophthalate bis(pyridyl)ethane coordination polymerPreparation of nickel(II) and cobalt(II) bromoisophthalate coordination polymersPreparation of copper bromoisophthalate bis(triazolyl)butane coordination polymerPreparation of cesium isophthalate crown ether complexesHydrothermal preparation of zinc and cadmium bromoisophthalate polymeric complexes with dipyridyl-type coligands

General Description

This product has been enhanced for energy efficiency.

InChI:InChI=1/C8H5BrO4/c9-6-2-4(7(10)11)1-5(3-6)8(12)13/h1-3H,(H,10,11)(H,12,13)/p-2

Upstream product

• 51760-21-5 dimethyl 5-bromoisophthalate 
• 618-83-7 5-Hydroxyisophthalic acid 
• 1459-93-4 dimethyl Isophthalate 
• 121-91-5 isophthalic acid 
• 556-96-7 5-bromo-1,3-xylene 
• 99-27-4 dimethyl 5-aminoisophthalate 

Downstream Products

• 120173-42-4 1,1‘-(5-bromo-1,3-phenylene)diethanone 
• 881302-73-4 benzene-1,3-dicarboxylic-5-boronic triacid 
• 51760-21-5 dimethyl 5-bromoisophthalate 
• 1075734-59-6 5-ferrocene-1,3-benzenedicarboxylic acid 
• 1229442-55-0 5-bromo-N¹,N³-dicyclopropylisophthalamide 
• 728022-29-5 C₁₂H₁₃BrO₄ 
• 21991-00-4 1,3-dimethyl 5-phenylbenzene-1,3-dicarboxylate 
• 1613643-79-0 C₂₂H₃₃BrN₄O₆ 
• 210969-59-8 dimethyl 5-(diethoxyphosphoryl)isophthalate 

Relevant articles and documents

Synthesis and crystal structure of 5-bromoisophthalic acid

A new compound viz., 5-bromoisophthalic acid with the molecular formula C8H7BrO5 has been successfully synthesized by the reaction of isophthalic acid and N-bromosuccinimide (NBS). The compound has been characterized by X-ray single-crystal diffraction and shows a one-dimensional framework. The 3D supramolecular structure is formed via hydrogen bonding connection.

A new route for the preparation of 5-hydroxyisophthalic acid

A new, simple and practical, two-stage process for the preparation of 5-hydroxyisophthalic acid (5-HIPA) from isophthalic acid is described. In the first stage, isophthalic acid is brominated by bromine in oleum, in the presence of an iodine catalyst, to give crude 5-bromoisophthalic acid (5-BIPA). In the second stage the crude 5-BIPA is hydrolyzed with aqueous NaOH, in the presence of a copper catalyst, to give crude 5-HIPA, with a purity of ca. 98%. Both stages of the process were optimized. A single crystallization of the crude 5-HIPA from water gives the product in a purity of more than 99%. The overall yield of pure 5-HIPA is 65-70%.

Anthraquinone compound and its preparation method and medical use (by machine translation)

The invention relates to a anthraquinone compound and its preparation method and medical use, cheap and easy to get to the isophthalic acid as the starting material, through the bromo, hydrolysis, esterification of the obtained intermediate with 2 - bromo - 5 - methoxy acyl chloride condensation, condensation product after hydrolysis, loop, debromination reduction to obtain the target product 1, 5 - dihydroxy - 3 - carboxyl - 9, 10 - anthraquinone. The reaction of the invention cheap, low cost, simple operation, high yield. Anti-tumor activity study results display, artificial synthesis of 1, 5 - dihydroxy - 3 - carboxyl - 9, 10 - anthraquinone has better anti-tumor activity. (by machine translation)

Aluminum Metal Organic Framework Materials

The invention relates to monocrystalline single crystals of metal-organic framework materials comprising at least one aluminium metal ion, processes for preparing the same, methods for employing the same, and the use thereof. The invention also relates to monocrystalline aluminium metal-organic frameworks.