[5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one

Base Information

• Chemical Name: [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one
• CAS No.: 76375-62-7
• Molecular Formula: C₉H₁₂O₄
• Molecular Weight: 184.192
• Hs Code.: 2932209090
• Mol file: 76375-62-7.mol

Synonyms:2(5H)-Furanone,5-(1-hydroxyethyl)-3-(3-methyloxiranyl)-, [2S-[2a[S*(R*)],3b]]-; 2(5H)-Furanone,5-[(1S)-1-hydroxyethyl]-3-[(2S,3S)-3-methyloxiranyl]-, (5R)- (9CI);Asperlactone

Chemical Property of [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one

Chemical Property:

• Vapor Pressure: 2.24E-07mmHg at 25°C
• Boiling Point: 381.1°C at 760 mmHg
• Flash Point: 158.3°C
• PSA: 59.06000
• Density: 1.329g/cm³
• LogP: 0.00630

Purity/Quality:

98%Min ^*data from raw suppliers

Asperlactone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Asperlactone is a biologically active polyketide metabolite produced mainly from aspergillus.

Technology Process of [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one

There total 2 articles about [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aspyrone (17398-00-4) → B9-chloro-8-hydroxy-8,9-deoxyaspyrone (1043452-75-0,664354-71-6) + (8R,9S)-8-chloro-9-hydroxy-8,9-deoxyaspyrone (1043452-74-9) + asperlactone (76375-62-7)

Guidance literature:

With hydrogenchloride; In chloroform; water; at 0 ℃; for 0.5h;

DOI:10.1021/np800107c

Reference yield:

<2-(2)H3,2-(13)C>acetic acid (79562-15-5) → asperlactone (76375-62-7)

Guidance literature:

With Aspergillus melleus IMI 49108; for 408h; Mechanism;

DOI:10.1039/c39810000708

Reference yield: 41.0%

phenyl isocyanate (103-71-9) + asperlactone (76375-62-7) → Phenyl-carbamic acid (S)-1-[(R)-4-((2S,3S)-3-methyl-oxiranyl)-5-oxo-2,5-dihydro-furan-2-yl]-ethyl ester (91793-94-1)

Guidance literature:

In chloroform; for 48h;

upstream raw materials:

<2-(2)H3,2-(13)C>acetic acid

aspyrone

Downstream raw materials:

Phenyl-carbamic acid (S)-1-[(R)-4-((2S,3S)-3-methyl-oxiranyl)-5-oxo-2,5-dihydro-furan-2-yl]-ethyl ester

4-Nitro-benzoic acid (S)-1-[(R)-4-((2S,3S)-3-methyl-oxiranyl)-5-oxo-2,5-dihydro-furan-2-yl]-ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 76375-62-7 [5R,(+)]-5-[(S)-1-Hydroxyethyl]-3-[(2S)-3-methyloxirane-2-yl]furan-2(5H)-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send