3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester

Base Information

• Chemical Name: 3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester
• CAS No.: 358365-78-3
• Molecular Formula: C₃₂H₃₇N₅O₁₂S₂
• Molecular Weight: 747.804
• Mol file: 358365-78-3.mol

Synonyms:

Chemical Property of 3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester

There total 1 articles about 3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1⁽¹⁶⁾,12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

methyl 3,5-bis(bromomethyl)benzoate (29333-41-3) + [2-(2-Nitro-benzenesulfonylamino)-ethyl]-[3-(2-nitro-benzenesulfonylamino)-propyl]-carbamic acid tert-butyl ester (182576-25-6) → 3,10-bis-(2-nitro-benzenesulfonyl)-3,6,10-triaza-bicyclo[10.3.1]hexadeca-1(16),12,14-triene-6,14-dicarboxylic acid 6-tert-butyl ester 14-methyl ester (358365-78-3)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/S0960-894X(01)00237-2

upstream raw materials:

methyl 3,5-bis(bromomethyl)benzoate

[2-(2-Nitro-benzenesulfonylamino)-ethyl]-[3-(2-nitro-benzenesulfonylamino)-propyl]-carbamic acid tert-butyl ester