ribavirin

Base Information

• Chemical Name: ribavirin
• CAS No.: 40372-11-0
• Molecular Formula: C₈H₁₂N₄O₅
• Molecular Weight: 244.207
• Mol file: 40372-11-0.mol

Synonyms:

Chemical Property of ribavirin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ribavirin

There total 3 articles about ribavirin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ ribavirin (36791-04-5,40372-02-9,40372-11-0,57198-01-3,57198-02-4,66510-90-5)

Guidance literature:

Carboxamid 8a, CF3COOH;

Reference yield:

α,β-D-arabinofuranose-5-phosphate disodium salt (108321-99-9,150713-51-2) + 1,2,4-triazole-3-carboxamide (3641-08-5) → 1-(β-D-Arabinofuranosyl)-<1,2,4>triazol-3-carboxamid (40372-11-0,66510-90-5)

Guidance literature:

With 2-hydroxyethanethiol; manganese(ll) chloride; purine nucleoside phosphorylase; In various solvent(s); at 45 ℃; for 72h; pH=7;

DOI:10.1016/j.tetlet.2008.02.087

Reference yield:

→ 1-(β-D-Arabinofuranosyl)-<1,2,4>triazol-3-carboxamid (40372-11-0,66510-90-5)

Guidance literature:

D-Arabinofuranosyl-chlorid, entspr. Triazol;

upstream raw materials:

α,β-D-arabinofuranose-5-phosphate disodium salt

1,2,4-triazole-3-carboxamide