allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Base Information

Chemical Name:allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate
CAS No.:1275617-02-1
Molecular Formula:C₂₈H₄₃BrN₄O₆SSi
Molecular Weight:671.728
Hs Code.:

allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Synonyms:

Suppliers and Price of allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

There total 10 articles about allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1275617-08-7
allyl 2-[(R)-2-amino-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-6-bromo-3-[dimethyl(thexyl)silyloxy]-5-methoxybenzoate

: 1275617-02-1
allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,2-dichloro-ethane / acetonitrile / 5 h / 0 °C / Inert atmosphere

2: trifluoroacetic acid / 0.17 h / 20 °C / Inert atmosphere

With 1,2-dichloro-ethane; trifluoroacetic acid; In acetonitrile;
DOI:10.1021/jm1014023

Reference yield:

: C₃₃H₅₁BrN₄O₈SSi

: 1275617-02-1
allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Guidance literature:: With trifluoroacetic acid; at 20 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1021/jm1014023

Reference yield:

: C₃₀H₄₆BrN₃O₇SSi

: 1275617-02-1
allyl 2-bromo-5-[dimethyl(thexyl)silyloxy]-3-methoxy-6-[(R)-2-(2-methylaminoacetylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)-ethylsulfanylmethyl]benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / 0.5 h / 0 °C / Inert atmosphere

2: 1,2-dichloro-ethane / acetonitrile / 5 h / 0 °C / Inert atmosphere

3: trifluoroacetic acid / 0.17 h / 20 °C / Inert atmosphere

With 1,2-dichloro-ethane; trifluoroacetic acid; In acetonitrile;
DOI:10.1021/jm1014023