tert-Butyl 2,6-dimethylpiperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 2,6-dimethylpiperidine-1-carboxylate
CAS No.:105678-29-3
Molecular Formula:C12H23NO2
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID00562951
Nikkaji Number:J2.216.997A
Mol file:105678-29-3.mol

Synonyms:105678-29-3;tert-Butyl 2,6-dimethylpiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 2,6-dimethyl-, 1,1-dimethylethyl ester;1-Boc-2,6-dimethylpiperidine;SCHEMBL2909390;DTXSID00562951;AKOS013217055;AS-76047;CS-0293146;D93305;tert-Butyl2,6-dimethylpiperidine-1-carboxylate;EN300-1126976

Suppliers and Price of tert-Butyl 2,6-dimethylpiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of tert-Butyl 2,6-dimethylpiperidine-1-carboxylate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:213.172878976
Heavy Atom Count:15
Complexity:222

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CCCC(N1C(=O)OC(C)(C)C)C

Technology Process of tert-Butyl 2,6-dimethylpiperidine-1-carboxylate

There total 2 articles about tert-Butyl 2,6-dimethylpiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₁H₂₀NO₂⁽¹⁺⁾

: 75-24-1
trimethylaluminum

: N-Boc-cis-2,6-dimethylpiperidine

: 105678-29-3,126503-24-0
N-Boc-trans-2,6-dimethylpiperidine

Guidance literature:: In hexane; dichloromethane; at -78 ℃; for 0.0833333h; Overall yield = 15.8 mg; diastereoselective reaction; Inert atmosphere;
DOI:10.3762/bjoc.14.100

Reference yield:

: 126503-04-6
tert-butyl 2-methylpiperidine-1-carboxylate

: 77-78-1
dimethyl sulfate

: 105678-29-3,126503-24-0
N-Boc-trans-2,6-dimethylpiperidine

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; Yield given. Multistep reaction; 1.) ether, -20 deg C; 2.) -78 deg C to r.t.;
DOI:10.1021/jo00296a008