N,N'-bis(2,4,6-trimethylphenyl)propanediamide

Base Information

• Chemical Name: N,N'-bis(2,4,6-trimethylphenyl)propanediamide
• CAS No.: 105678-72-6
• Molecular Formula: C₂₁H₂₆N₂O₂
• Molecular Weight: 338.45
• DSSTox Substance ID: DTXSID701248197
• Mol file: 105678-72-6.mol

Synonyms:N,N'-bis(2,4,6-trimethylphenyl)propanediamide;105678-72-6;Oprea1_369596;CBDivE_012226;DTXSID701248197;AKOS001035452;N1,N3-Bis(2,4,6-trimethylphenyl)propanediamide;SR-01000401435;SR-01000401435-1;F1708-0005

Chemical Property of N,N'-bis(2,4,6-trimethylphenyl)propanediamide

Chemical Property:

• XLogP3: 5.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 338.199428076
• Heavy Atom Count: 25
• Complexity: 413

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)C)NC(=O)CC(=O)NC2=C(C=C(C=C2C)C)C)C

Technology Process of N,N'-bis(2,4,6-trimethylphenyl)propanediamide

There total 1 articles about N,N'-bis(2,4,6-trimethylphenyl)propanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trimethylaniline (88-05-1) + diethyl malonate (105-53-3) → malonic acid bis-(2,4,6-trimethyl-anilide) (105678-72-6)

Guidance literature:

DOI:10.1007/BF00905674

Reference yield: 56.0%

malonic acid bis-(2,4,6-trimethyl-anilide) (105678-72-6) → bismesityldichloromalonimidoyl dichloride (105678-78-2)

Guidance literature:

With phosphorus pentachloride; In toluene; for 5h; Heating;

upstream raw materials:

2,4,6-trimethylaniline

diethyl malonate

Downstream raw materials:

bismesityldichloromalonimidoyl dichloride