europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid

Base Information

• Chemical Name: europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid
• CAS No.: 1609488-33-6
• Molecular Formula: C₂₄H₂₅EuN₄O₆
• Molecular Weight: 617.446
• Mol file: 1609488-33-6.mol

Synonyms:

Chemical Property of europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid

There total 5 articles about europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

europium(III) chloride hexahydrate + C24H28N4O6 → europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid (1609488-33-6)

Guidance literature:

With sodium hydrogencarbonate; In water; at 20 ℃; for 2h;

DOI:10.1002/chem.201304942

Reference yield:

diethyl 2,2'-{[(4-{[4-(dimethylamino)phenyl]ethynyl}-6-{[(2-methoxy-2-oxoethyl)(methyl)amino]methyl}pyridin-2-yl)methyl]azanediyl}diacetate (1609476-23-4) → europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid (1609488-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / methanol / 3 h / Reflux

2: sodium hydrogencarbonate / water / 2 h / 20 °C

With hydrogenchloride; sodium hydrogencarbonate; In methanol; water;

DOI:10.1002/chem.201304942

Reference yield:

diethyl 2,2'-(((4-bromo-6-(bromomethyl)pyridin-2-yl)methyl)azanediyl)diacetate (1444764-51-5) → europium(III)-2,2'-(((6-(((carboxymethyl)(methyl)amino)methyl)-4-((4-(dimethylamino)phenyl)ethynyl)pyridin-2-yl)methyl)azanediyl)diacetic acid (1609488-33-6)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / acetonitrile / 20 h / Reflux

2: triethylamine; trans-bis(triphenylphosphine)palladium dichloride; copper(l) iodide / tetrahydrofuran / 54 °C / Inert atmosphere

3: hydrogenchloride / methanol / 3 h / Reflux

4: sodium hydrogencarbonate / water / 2 h / 20 °C

With hydrogenchloride; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; sodium hydrogencarbonate; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; water; acetonitrile;

DOI:10.1002/chem.201304942

upstream raw materials:

diethyl 2,2'-{[(4-{[4-(dimethylamino)phenyl]ethynyl}-6-{[(2-methoxy-2-oxoethyl)(methyl)amino]methyl}pyridin-2-yl)methyl]azanediyl}diacetate

4-bromo-2,6-bis(bromomethyl)pyridine

diethyl 2,2'-(((4-bromo-6-(bromomethyl)pyridin-2-yl)methyl)azanediyl)diacetate

diethyl 2,2'-{[(4-bromo-6-{[(2-methoxy-2-oxoethyl)(methyl)amino]methyl}pyridin-2-yl)methyl]azanediyl}diacetate