N-(3-chlorobenzylidene)pyridine-2-sulfonamide

Base Information

• Chemical Name: N-(3-chlorobenzylidene)pyridine-2-sulfonamide
• CAS No.: 1191396-24-3
• Molecular Formula: C₁₂H₉ClN₂O₂S
• Molecular Weight: 280.735
• Mol file: 1191396-24-3.mol

Synonyms:

Chemical Property of N-(3-chlorobenzylidene)pyridine-2-sulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-(3-chlorobenzylidene)pyridine-2-sulfonamide

There total 1 articles about N-(3-chlorobenzylidene)pyridine-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-pyridinesulfonamide (63636-89-5) + m-Chlorobenzaldehyde (587-04-2) → N-(3-chlorobenzylidene)pyridine-2-sulfonamide (1191396-24-3)

Guidance literature:

With Amberlyst 15; In toluene; for 14h; Inert atmosphere; Molecular sieve; Reflux;

DOI:10.1002/chem.200900496

Reference yield:

perfluoro-1-butanesulfonyl fluoride (2386-60-9) + N-(3-chlorobenzylidene)pyridine-2-sulfonamide (1191396-24-3) → 3-(3-chlorophenyl)-4-propyl-2-(2-pyridylsulfonyl)-1,2-thiazetidine-1,1-dioxide

Guidance literature:

With Quinuclidine; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -80 ℃; for 20h; optical yield given as %de; Inert atmosphere;

DOI:10.1002/chem.200900496

Reference yield:

pyrrole (109-97-7,30604-81-0) + N-(3-chlorobenzylidene)pyridine-2-sulfonamide (1191396-24-3) → C16H14ClN3O2S + C16H14ClN3O2S

Guidance literature:

With (R)-3,3'-bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; In toluene; at 20 ℃; for 12h; enantioselective reaction;

DOI:10.1055/s-0029-1217324

upstream raw materials:

2-pyridinesulfonamide

m-Chlorobenzaldehyde

Downstream raw materials:

(3S,4S)-3-(3-chlorophenyl)-4-propyl-2-(2-pyridylsulfonyl)-1,2-thiazetidine-1,1-dioxide

(3R)-(2-pyridinesulfonyl)amino-3-(3-chlorophenyl)propionitrile