(R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride

Base Information

Chemical Name:(R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride
CAS No.:1332593-91-5
Molecular Formula:C₈H₉ClFN*ClH
Molecular Weight:210.079
Hs Code.:
European Community (EC) Number:865-353-2
DSSTox Substance ID:DTXSID60704133

Synonyms:(R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride;1217464-96-4;1332593-91-5;(1R)-1-(5-CHLORO-2-FLUOROPHENYL)ETHYLAMINE-HCl;(1R)-1-(5-chloro-2-fluorophenyl)ethan-1-amine hydrochloride;(1R)-1-(5-chloro-2-fluorophenyl)ethanamine;hydrochloride;(1r)-1-(5-chloro-2-fluorophenyl)ethylamine hydrochloride;SCHEMBL19613457;(R)-1-(5-Chloro-2-fluorophenyl)-ethanamine hydrochloride;DTXSID60704133;ZJWNGZJNOWRDLV-NUBCRITNSA-N;MFCD16294082;AKOS015922856;AKOS016009421;BS-14912;CS-0158212;EN300-122349;(R)-1-(5-Chloro-2-fluorophenyl)ethanamine HCl;(1r)-1-(5-chloro-2-fluorophenyl)ethylamine HCl;(R)-1-(5-Chloro-2-fluorophenyl)ethanaminehydrochloride;(1R)-1-(5-Chloro-2-fluorophenyl)ethan-1-amine--hydrogen chloride (1/1);Benzenemethanamine, 5-chloro-2-fluoro-alpha-methyl-, hydrochloride (1:1), (alphaR)-

Suppliers and Price of (R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:209.0174329
Heavy Atom Count:12
Complexity:131

Purity/Quality:: 95-3545%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=C(C=CC(=C1)Cl)F)N.Cl
Isomeric SMILES:C[C@H](C1=C(C=CC(=C1)Cl)F)N.Cl

Technology Process of (R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride

There total 3 articles about (R)-1-(5-Chloro-2-fluorophenyl)ethanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (S)-N-((R)-1-(5-chloro-2-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide

: 1332593-91-5,1423040-76-9
(R)-1-(5-chloro-2-fluorophenyl)ethan-1-amine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 2h;

Reference yield:

: (S,E)-N-(5-chloro-2-fluorobenzylidene)-2-methylpropane-2-sulfinamide

: 1332593-91-5,1423040-76-9
(R)-1-(5-chloro-2-fluorophenyl)ethan-1-amine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane; diethyl ether / 2 h / -78 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

With hydrogenchloride; In 1,4-dioxane; diethyl ether; dichloromethane;

Reference yield:

: 96515-79-6
5-chloro-2-fluorobenzaldehyde

: 1332593-91-5,1423040-76-9
(R)-1-(5-chloro-2-fluorophenyl)ethan-1-amine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: titanium(IV) isopropylate / dichloromethane / 18 h / 20 °C

2: dichloromethane; diethyl ether / 2 h / -78 - 20 °C

3: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

With titanium(IV) isopropylate; hydrogenchloride; In 1,4-dioxane; diethyl ether; dichloromethane;