Technology Process of 1-(3-chloropropyl)-4-phenyl-1,5-diazacyclononan-2-one
There total 7 articles about 1-(3-chloropropyl)-4-phenyl-1,5-diazacyclononan-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
for 20h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / diethyl ether / 1 h / Ambient temperature
2: 88 percent / 25percent aq. sodium sulfite, 10percent aq. KOH / diethyl ether; CHCl3 / 1 h
3: 69 percent / KOH, DMSO / 23 h
4: 67 percent / NH3 liquid / 120 h / 55 °C
5: 39 percent / potassium bis(trimethylsilyl)amide / tetrahydrofuran / 20 h
With
potassium hydroxide; ammonia; potassium hexamethylsilazane; dimethyl sulfoxide; sodium sulfite;
In
tetrahydrofuran; diethyl ether; chloroform;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 88 percent / 25percent aq. sodium sulfite, 10percent aq. KOH / diethyl ether; CHCl3 / 1 h
2: 69 percent / KOH, DMSO / 23 h
3: 67 percent / NH3 liquid / 120 h / 55 °C
4: 39 percent / potassium bis(trimethylsilyl)amide / tetrahydrofuran / 20 h
With
potassium hydroxide; ammonia; potassium hexamethylsilazane; dimethyl sulfoxide; sodium sulfite;
In
tetrahydrofuran; diethyl ether; chloroform;
