4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Base Information

Chemical Name:4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester
CAS No.:1091682-36-8
Molecular Formula:C₃₀H₄₆N₄O₆
Molecular Weight:558.718
Hs Code.:

4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Synonyms:

Suppliers and Price of 4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

There total 8 articles about 4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₅H₅₈N₄O₈

: 1091682-36-8
4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃;
DOI:10.1016/j.bmcl.2016.04.086

Reference yield:

: C₂₂H₂₆N₂O₄*ClH

: 1091682-36-8
4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

2: hydrogenchloride / water; ethyl acetate / 20 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

4: hydrogen; palladium on activated charcoal / ethanol / 20 °C

With hydrogenchloride; dmap; palladium on activated charcoal; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/j.bmcl.2016.04.086

Reference yield:

: C₂₇H₃₄N₂O₆

: 1091682-36-8
4-[(1-{(S)-2-[(R)-2-cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionylamino]-3,3-dimethyl-butyryl}-piperidin-4-ylamino)-methyl]-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: hydrogenchloride / water; ethyl acetate / 20 °C

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

3: hydrogenchloride / water; ethyl acetate / 20 °C

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

5: hydrogen; palladium on activated charcoal / ethanol / 20 °C

With hydrogenchloride; dmap; palladium on activated charcoal; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/j.bmcl.2016.04.086