C₄₁H₅₄N₆O₉S

Base Information

• Chemical Name: C₄₁H₅₄N₆O₉S
• CAS No.: 143217-84-9
• Molecular Formula: C₄₁H₅₄N₆O₉S
• Molecular Weight: 806.981
• Mol file: 143217-84-9.mol

Synonyms:

Chemical Property of C₄₁H₅₄N₆O₉S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₅₄N₆O₉S

There total 7 articles about C₄₁H₅₄N₆O₉S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C41H54N6O9S (143217-84-9,143217-85-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

2: 94 percent / DCC / 1,2-dimethoxy-ethane / 4 h

3: 92 percent / NaHCO₃ / H₂O; 1,2-dimethoxy-ethane / 3 h / Ambient temperature

4: DCC / 1,2-dimethoxy-ethane / 3 h / Ambient temperature

5: Et₃N / dimethylformamide; 1,2-dimethoxy-ethane / Ambient temperature

With sodium hydroxide; sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jm00096a010

Reference yield:

ethyl acetamido(diphenylmethyl)cyanoacetate (143646-43-9) → C41H54N6O9S (143217-84-9,143217-85-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 82 percent / 20percent aq. HCl / 30 h / Heating

2: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

3: 94 percent / DCC / 1,2-dimethoxy-ethane / 4 h

4: 92 percent / NaHCO₃ / H₂O; 1,2-dimethoxy-ethane / 3 h / Ambient temperature

5: DCC / 1,2-dimethoxy-ethane / 3 h / Ambient temperature

6: Et₃N / dimethylformamide; 1,2-dimethoxy-ethane / Ambient temperature

With hydrogenchloride; sodium hydroxide; sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jm00096a010

Reference yield:

2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid (119363-63-2) → C41H54N6O9S (143217-84-9,143217-85-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / DCC / 1,2-dimethoxy-ethane / 4 h

2: 92 percent / NaHCO₃ / H₂O; 1,2-dimethoxy-ethane / 3 h / Ambient temperature

3: DCC / 1,2-dimethoxy-ethane / 3 h / Ambient temperature

4: Et₃N / dimethylformamide; 1,2-dimethoxy-ethane / Ambient temperature

With sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jm00096a010

upstream raw materials:

L-Arg(Mtr)

(S)-1-(2-tert-Butoxycarbonylamino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester

di-tert-butyl dicarbonate

ethyl acetamido(diphenylmethyl)cyanoacetate

Downstream raw materials:

C₄₅H₆₀N₆O₁₀S

C₄₄H₅₈N₆O₁₀S

C₄₉H₆₇N₇O₉S

(S)-1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid [1-(3-guanidino-propyl)-2,5-dioxo-5-piperidin-1-yl-pentyl]-amide; compound with trifluoro-acetic acid