C₄₅H₅₅N₉O₈

Base Information

• Chemical Name: C₄₅H₅₅N₉O₈
• CAS No.: 946847-92-3
• Molecular Formula: C₄₅H₅₅N₉O₈
• Molecular Weight: 849.987
• Mol file: 946847-92-3.mol

Synonyms:

Chemical Property of C₄₅H₅₅N₉O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₅H₅₅N₉O₈

There total 12 articles about C₄₅H₅₅N₉O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H40N2O9S → C45H55N9O8 (946847-92-3)

Guidance literature:

Multi-step reaction with 8 steps

1: NaN₃ / dimethylformamide / 90 °C

2: aq. LiOH / dioxane

3: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

4: 80 percent / CuSO₄*5H₂O; sodium ascorbate / H₂O; 2-methyl-propan-2-ol

5: aq. LiOH / dioxane

6: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

7: aq. HCl

8: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

With hydrogenchloride; lithium hydroxide; sodium azide; benzotriazol-1-ol; copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2007.04.096

Reference yield:

C24H40N6O7 (946847-87-6) → C45H55N9O8 (946847-92-3)

Guidance literature:

Multi-step reaction with 3 steps

1: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

2: aq. HCl

3: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1016/j.bmcl.2007.04.096

Reference yield:

C19H35N5O6 (946847-81-0) → C45H55N9O8 (946847-92-3)

Guidance literature:

Multi-step reaction with 6 steps

1: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

2: 80 percent / CuSO₄*5H₂O; sodium ascorbate / H₂O; 2-methyl-propan-2-ol

3: aq. LiOH / dioxane

4: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

5: aq. HCl

6: EDCI; HOBt; i-Pr₂NEt / CH₂Cl₂

With hydrogenchloride; lithium hydroxide; benzotriazol-1-ol; copper(II) sulfate; sodium L-ascorbate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; water; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2007.04.096

upstream raw materials:

C₂₄H₃₄N₈O₅

Fmoc-Leu-OH

C₂₄H₄₀N₆O₇

C₃₃H₅₀N₈O₇

Downstream raw materials:

C₅₅H₇₇N₁₀O₁₃P