C₂₄H₂₀N₂O₃S

Base Information

• Chemical Name: C₂₄H₂₀N₂O₃S
• CAS No.: 1352537-23-5
• Molecular Formula: C₂₄H₂₀N₂O₃S
• Molecular Weight: 416.5
• Mol file: 1352537-23-5.mol

Synonyms:

Chemical Property of C₂₄H₂₀N₂O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₀N₂O₃S

There total 15 articles about C₂₄H₂₀N₂O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Bromopyridine (626-55-1,163928-56-1) + C19H17NO4S (1352536-90-3) → C24H20N2O3S (1352537-24-6) + C24H20N2O3S (1352537-23-5)

Guidance literature:

3-Bromopyridine; With lithium hexamethyldisilazane; In tetrahydrofuran; at -15 ℃; Inert atmosphere; Reflux;

C₁₉H₁₇NO₄S; Inert atmosphere;

With diiron nonacarbonyl; In benzene; for 15h; Inert atmosphere;

DOI:10.1016/j.tet.2011.10.022

Reference yield:

4-methoxy-phenyl-sulphonyl chloride (98-68-0) → C24H20N2O3S (1352537-24-6) + C24H20N2O3S (1352537-23-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere; Cooling with ice

2.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Reflux

3.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

3.3: Inert atmosphere

4.1: Amberlyst-15 acid ion-exchange resin / water; isopropyl alcohol / Inert atmosphere

5.1: lithium hexamethyldisilazane / tetrahydrofuran / -15 °C / Inert atmosphere; Reflux

5.2: Inert atmosphere

5.3: 15 h / Inert atmosphere

With sodium hydride; toluene-4-sulfonic acid; lithium hexamethyldisilazane; lithium diisopropyl amide; In tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol; toluene; 5.2: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.10.022

Reference yield:

3-acetylindole (703-80-0) → C24H20N2O3S (1352537-24-6) + C24H20N2O3S (1352537-23-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere; Cooling with ice

2.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Reflux

3.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

3.3: Inert atmosphere

4.1: Amberlyst-15 acid ion-exchange resin / water; isopropyl alcohol / Inert atmosphere

5.1: lithium hexamethyldisilazane / tetrahydrofuran / -15 °C / Inert atmosphere; Reflux

5.2: Inert atmosphere

5.3: 15 h / Inert atmosphere

With sodium hydride; toluene-4-sulfonic acid; lithium hexamethyldisilazane; lithium diisopropyl amide; In tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol; toluene; 5.2: Diels-Alder reaction;

DOI:10.1016/j.tet.2011.10.022

upstream raw materials:

3-Bromopyridine

C₁₉H₁₇NO₄S

3-acetylindole

Indole-2-carboxylic acid