homobiotin tosylate

Base Information

• Chemical Name: homobiotin tosylate
• CAS No.: 1379655-82-9
• Molecular Formula: C₁₈H₂₆N₂O₄S₂
• Molecular Weight: 398.547
• Mol file: 1379655-82-9.mol

Synonyms:

Chemical Property of homobiotin tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of homobiotin tosylate

There total 5 articles about homobiotin tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-Homobiotinmethylester (69705-13-1) → homobiotin tosylate (1379655-82-9)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran

2: pyridine

With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/ml300106p

Reference yield:

D-homobiotin (1784-22-1,5518-88-7) → homobiotin tosylate (1379655-82-9)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride

2: lithium aluminium tetrahydride / tetrahydrofuran

3: pyridine

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;

DOI:10.1021/ml300106p

Reference yield:

5-((3a5,45,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl 4-methylbenzenesulfonate (69705-14-2) → homobiotin tosylate (1379655-82-9)

Guidance literature:

Multi-step reaction with 5 steps

1: N,N-dimethyl-formamide / 20 °C

2: sodium hydroxide; water / Reflux

3: thionyl chloride

4: lithium aluminium tetrahydride

5: pyridine

With pyridine; lithium aluminium tetrahydride; thionyl chloride; water; sodium hydroxide; In N,N-dimethyl-formamide;

upstream raw materials:

(+)-Homobiotinmethylester

C₁₁H₂₀N₂O₂S

p-toluenesulfonyl chloride

D-homobiotin