biotin tosylate

Base Information

Chemical Name:biotin tosylate
CAS No.:69705-14-2
Molecular Formula:C17H24N2O6S2
Molecular Weight:384.521
Hs Code.:

Synonyms:biotin tosylate;(3aS,4S,6aR)-Tetrahydro-4-[5-[[(4-methylphenyl)sulfonyl]oxy]pentyl]-1H-thieno[3,4-d]imidazol-2(3H)-one

Suppliers and Price of biotin tosylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of biotin tosylate

Chemical Property:

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of biotin tosylate

There total 5 articles about biotin tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 98-59-9
p-toluenesulfonyl chloride

: 53906-36-8
1H-thieno<3,4-d>imidazol-2(3H)-one, tetrahydro-4-(5-hydroxypentyl)-, <3aS-(3aα,4β,6aα)>-

: 69705-14-2
5-((3a5,45,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl 4-methylbenzenesulfonate

Guidance literature:: With pyridine;
DOI:10.1021/ol060458r

Reference yield:

: 58-85-5,22879-79-4
biotin

: 69705-14-2
5-((3a5,45,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride

2: lithium aluminium tetrahydride / tetrahydrofuran

3: pyridine / dichloromethane

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja108258d

Reference yield:

: 87573-52-2
5-[(3aS,4S,6aR)-2-oxo-hexahydro-thieno[3,4-d]imidazol-4-yl]-pentanoic acid ethyl ester

: 69705-14-2
5-((3a5,45,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / diisobutylaluminum hydride / CH₂Cl₂ / 1.83 h / -78 - 20 °C

2: 94 percent / pyridine

With pyridine; diisobutylaluminium hydride; In dichloromethane;
DOI:10.1021/ol060458r