C₁₇H₂₀N₂O₃

Base Information

• Chemical Name: C₁₇H₂₀N₂O₃
• CAS No.: 1354834-75-5
• Molecular Formula: C₁₇H₂₀N₂O₃
• Molecular Weight: 300.357
• Mol file: 1354834-75-5.mol

Synonyms:

Chemical Property of C₁₇H₂₀N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₀N₂O₃

There total 6 articles about C₁₇H₂₀N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) → C17H20N2O3 (1354834-75-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: triethylamine; magnesium chloride / dichloromethane / 30 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: pyridine / 0.33 h / 100 °C / Inert atmosphere

3.1: palladium on activated charcoal; hydrogen; triethylamine / ethanol / 16 h / 2585.81 Torr

4.1: ammonium acetate; water / methanol / 16 h / 20 °C

5.1: trifluoroacetic acid / dichloromethane / 2 h

With pyridine; palladium on activated charcoal; ammonium acetate; water; hydrogen; triethylamine; trifluoroacetic acid; magnesium chloride; In methanol; ethanol; dichloromethane;

DOI:10.1021/ja203483j

Reference yield:

N-(tert-butoxycarbonyl)-L-tyrosine ethyl ester (72594-77-5,1241680-28-3) → C17H20N2O3 (1354834-75-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: triethylamine; magnesium chloride / dichloromethane / 30 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: pyridine / 0.33 h / 100 °C / Inert atmosphere

3.1: palladium on activated charcoal; hydrogen; triethylamine / ethanol / 16 h / 2585.81 Torr

4.1: ammonium acetate; water / methanol / 16 h / 20 °C

5.1: trifluoroacetic acid / dichloromethane / 2 h

With pyridine; palladium on activated charcoal; ammonium acetate; water; hydrogen; triethylamine; trifluoroacetic acid; magnesium chloride; In methanol; ethanol; dichloromethane;

DOI:10.1021/ja203483j

Reference yield:

ethyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-(hydroxy(pyridin-2-yl)-methyl)phenyl)propanoate (1328942-30-8) → C17H20N2O3 (1354834-75-5)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / 0.33 h / 100 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen; triethylamine / ethanol / 16 h / 2585.81 Torr

3: ammonium acetate; water / methanol / 16 h / 20 °C

4: trifluoroacetic acid / dichloromethane / 2 h

With pyridine; palladium on activated charcoal; ammonium acetate; water; hydrogen; triethylamine; trifluoroacetic acid; In methanol; ethanol; dichloromethane;

DOI:10.1021/ja203483j

upstream raw materials:

pyridine-2-carbaldehyde

ethyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-(hydroxy(pyridin-2-yl)-methyl)phenyl)propanoate

ethyl 3-(4-acetoxy-3-(acetoxy(pyridin-2-yl)methyl)-phenyl)-2-((tert-butoxycarbonyl)amino)propanoate

ethyl 3-(4-acetoxy-3-(pyridin-2-ylmethyl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoate