2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid

Base Information

• Chemical Name: 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid
• CAS No.: 1671080-26-4
• Molecular Formula: C₂₆H₁₉O₅P
• Molecular Weight: 442.408
• Mol file: 1671080-26-4.mol

Synonyms:

Chemical Property of 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid

There total 2 articles about 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

4-carboxyphenylboronic acid (14047-29-1) + 3-bromo-4-iodobenzoic acid (249647-25-4) + Diphenylphosphine oxide (4559-70-0) → 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid (1671080-26-4)

Guidance literature:

4-carboxyphenylboronic acid; 3-bromo-4-iodobenzoic acid; With palladium 10% on activated carbon; potassium carbonate; In water; for 18h;

Diphenylphosphine oxide; at 160 ℃; for 2.11667h; Microwave irradiation;

DOI:10.1002/chem.201404498

Reference yield:

4-iodobenzoic acid (619-58-9) → 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid (1671080-26-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid; N-Bromosuccinimide / 20 °C

2.1: palladium 10% on activated carbon; potassium carbonate / water / 18 h

2.2: 2.12 h / 160 °C / Microwave irradiation

With N-Bromosuccinimide; sulfuric acid; palladium 10% on activated carbon; potassium carbonate; In water;

DOI:10.1002/chem.201404498

Reference yield:

zinc nitrate tetrahydrate + 2-amino-[1,1′-biphenyl]-4,4′-dicarboxylic acid (1240557-01-0) + 2-(diphenylphosphoryl)-[1,1'-biphenyl]-4,4'-dicarboxylic acid (1671080-26-4) → [Zn4O(NH2-(1,1'-biphenyl)-4,4'-dicarboxylic acid)1.5(diphenylphosphoryl-(1,1'-biphenyl)-4,4'-dicarboxylic acid)1.5]

Guidance literature:

In N,N-dimethyl-formamide; at 85 ℃; for 72h;

DOI:10.1002/cctc.201402164

upstream raw materials:

4-carboxyphenylboronic acid

3-bromo-4-iodobenzoic acid

Diphenylphosphine oxide

4-iodobenzoic acid