Technology Process of 2-nitro-1-pentafluorophenylpropanol
There total 1 articles about 2-nitro-1-pentafluorophenylpropanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
at 20 ℃;
for 30h;
DOI:10.1016/j.tet.2006.04.046
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 29.3 g / DMAP / CH2Cl2 / 16 h
2: 16.38 g / tetramethylguanidine / tetrahydrofuran; propan-2-ol / 0 - 20 °C
3: 69 percent / acetic acid; hydrogen peroxide / CH2Cl2; H2O / 24 h / Heating
4: 95 percent / sodium borohydride / ethanol / 0.17 h
With
dmap; sodium tetrahydroborate; 1,1,3,3-tetramethylguanidine; dihydrogen peroxide; acetic acid;
In
tetrahydrofuran; ethanol; dichloromethane; water; isopropyl alcohol;
2: Barton-Zard reaction;
DOI:10.1016/j.tet.2006.04.046
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 29.3 g / DMAP / CH2Cl2 / 16 h
2: 16.38 g / tetramethylguanidine / tetrahydrofuran; propan-2-ol / 0 - 20 °C
3: 69 percent / acetic acid; hydrogen peroxide / CH2Cl2; H2O / 24 h / Heating
4: 95 percent / sodium borohydride / ethanol / 0.17 h
5: 71 percent / ethanol / 1 h / 10 °C
With
dmap; sodium tetrahydroborate; 1,1,3,3-tetramethylguanidine; dihydrogen peroxide; acetic acid;
In
tetrahydrofuran; ethanol; dichloromethane; water; isopropyl alcohol;
2: Barton-Zard reaction;
DOI:10.1016/j.tet.2006.04.046
